[1] Green MR,Chowdhary S,Lombardi KM,et al.Clinical utility and pharmacology of high-dose MTX in the treatment of primary CNS lymphoma[J].Expert Rev Neurother,2006,6(5):635-652.
[2] Lennard L.Therapeutic drug monitoring of antimetabolic cytotoxic drugs[J].Br J Clin Pharmacol,1999,47:131-143.
[3] 彭 波.高效液相色谱法测定甲氨蝶呤的血药浓度[J].中国医院药学杂志,2011, 31 (11):951-952.
[4] 张春燕,顾 健.反相高效液相色谱法同时测定人血浆中亚叶酸、5-甲基四氢叶酸及甲氨蝶呤的浓度及临床应用[J].中国药学杂志,2010,45(7):543-547.
[5] 许耘川,袁向亮,沈立松.HPLC法测定血清甲氨蝶呤浓度的方法建立及其与荧光偏振法的比较[J].检验医学,2010,25(9):701-704.
[6] 谢军平,冯玲玲,匡 霞.HPLC 测定大剂量甲氨蝶呤患者血药浓度[J].中国实验方剂学杂志,2010,16(11):69-72.
[7] 霍 晶,袁盛华,方 芸,等.反相高效液相色谱法测定人血浆中甲氨蝶呤的浓度[J].药学与临床研究,2007,15(5):390-392.
[8] Turci R,Micoli G,Minoia C.Determination of methotrexate in environmental samples by solid phase extraction and high performance liquid chromatography: ultraviolet or tandem mass spectrometry detection?[J].Rapid Commun Mass Spectr,2000,14:685-691.
[9] 周 卿,潘雪君.固相萃取-高效液相色谱法测定人乳中甲氨蝶呤的含量[J].药物分析杂志,2011,31(12):2305-2307.
[10] 吴雪梅, 丘宏强, 方令平, 等.固相萃取-高效液相色谱法测定甲氨蝶呤的血药浓度[J].中国医院药学杂志,2008,28(18):1617-1619.
[JP2]张华年,文玲莉,张少文, 等.固相萃取高效液相色谱法检测生物样本中甲氨喋呤[J].药物分析杂志,2000,20(6):401-404.
[12] 曹一辰,孟祥乐,朱金辉,等.LC-MS/MS法测定人血清中甲氨蝶呤及其代谢产物7-羟基甲氨蝶呤的浓度[J].中国药师,2012,15(2):191-194.
[13] Guo PI, Wang XM, Liu LS, et al.Determination of methotrexate and its major metabolite 7-hydroxymethotrexate in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry[J].J Pharm Biomed Anal,2007,43:1789-1795.