[1] |
LIBBY P, RIDKER P M, HANSSON G K. Progress and challenges in translating the biology of atherosclerosis[J]. Nature,2011,473(7347):317-325. doi: 10.1038/nature10146 |
[2] |
BENTZON J F, OTSUKA F, VIRMANI R, et al. Mechanisms of plaque formation and rupture[J]. Circ Res,2014,114(12):1852-1866. doi: 10.1161/CIRCRESAHA.114.302721 |
[3] |
KOETH R A, WANG Z, LEVISON B S, et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis[J]. Nat Med,2013,19(5):576-585. doi: 10.1038/nm.3145 |
[4] |
杜文婷, 王臻楠, 顾耘. 动脉粥样硬化的中西医认识概况[J]. 中西医结合心脑血管病杂志, 2016, 14(22):2634-2637. doi: 10.3969/j.issn.1672-1349.2016.22.014 |
[5] |
LIBBY P, BURING J E, BADIMON L, et al. Atherosclero-sis[J]. Nat Rev Dis Primers,2019,5(1):56. doi: 10.1038/s41572-019-0106-z |
[6] |
刘传亮, 陈国华, 李蕾. 复方丹参川芎中药配方颗粒干预老年颈动脉粥样硬化的研究[J]. 世界最新医学信息文摘, 2019, 19(82):15-16, 19. |
[7] |
梅琼, 李全胜, 张静, 等. 当归川芎组合对血脂及冠状动脉组织结构影响的实验研究[J]. 湖北中医药大学学报, 2015, 17(5):47-49. doi: 10.3969/j.issn.1008-987x.2015.05.16 |
[8] |
张燕, 李芳, 徐丽. 益气滋阴、活血通络复方对动脉粥样硬化患者LDL-C和HDL-C水平的影响[J]. 饮食保健, 2016, 3(10):72-73. |
[9] |
王磊, 姚淮芳. 复方三七护脉汤联合西医常规治疗心血瘀阻型冠心病稳定型心绞痛20例临床观察[J]. 甘肃中医药大学学报, 2019, 36(3):48-51. |
[10] |
MAGUIRE E M, PEARCE S W A, XIAO Q. Foam cell formation: a new target for fighting atherosclerosis and cardiovascular disease[J]. Vascul Pharmacol,2019,112:54-71. doi: 10.1016/j.vph.2018.08.002 |
[11] |
李杉杉, 申定珠, 陈川, 等. 以ABCA1为靶点的补肾中药复方防治动脉粥样硬化的思路探讨[J]. 中国中医急症, 2017, 26(5):834-837. doi: 10.3969/j.issn.1004-745X.2017.05.025 |
[12] |
王晓宁. 化浊通脉方对动脉粥样硬化兔胆固醇逆向转运的影响[D]. 北京: 北京中医药大学, 2015. |
[13] |
祝骥, 许颖龄, 卢德赵, 等. 复方丹参片对颈动脉粥样硬化兔PPAR-γ/LXR-α/ABCA1信号通路的影响[J]. 中国现代应用药学, 2016, 33(12):1503-1507. |
[14] |
秦合伟, 李彦杰, 任锟, 等. 基于miR-33a调控ABCA1表达探讨血管软化丸抗动脉粥样硬化的作用机制[J]. 中医药信息, 2018, 35(6):1-7. |
[15] |
许丽婷, 徐彬人, 盛蒙, 等. 黄连解毒汤含药血清对泡沫细胞ABCA1表达与胆固醇含量的影响[J]. 中国民族民间医药, 2020, 29(6):10-13. |
[16] |
HAO D, DANBIN W, MAOJUAN G, et al. Ethanol extracts of Danlou tablet attenuate atherosclerosis via inhibiting inflammation and promoting lipid effluent[J]. Pharmacol Res,2019,146:104306. doi: 10.1016/j.phrs.2019.104306 |
[17] |
HIGASHI Y, NOMA K, YOSHIZUMI M, et al. Endothelial function and oxidative stress in cardiovascular diseases[J]. Circ J,2009,73(3):411-418. doi: 10.1253/circj.CJ-08-1102 |
[18] |
KONDO T, HIROSE M, KAGEYAMA K. Roles of oxidative stress and redox regulation in atherosclerosis[J]. J Atheroscler Thromb,2009,16(5):532-538. doi: 10.5551/jat.1255 |
[19] |
GLIOZZI M, SCICCHITANO M, BOSCO F, et al. Modulation of nitric oxide synthases by oxidized ldls: role in vascular inflammation and atherosclerosis development[J]. International Journal of Molecular Sciences,2019,20(13):3294. doi: 10.3390/ijms20133294 |
[20] |
李红蓉, 常成成, 郭勇英, 等. 通心络对氧化低密度脂蛋白损伤血管内皮细胞的保护作用[J]. 医学研究生学报, 2015, 28(11):1128-1132. |
[21] |
汪玉成, 魏伟, 苏清平, 等. 泽泻汤对氧化型低密度脂蛋白诱导血管平滑肌细胞增殖的影响[J]. 中国动脉硬化杂志, 2016, 24(8):763-768. |
[22] |
王红梅, 周建明, 吕耀中, 等. 龙血通络胶囊对氧化低密度脂蛋白损伤人脐静脉内皮细胞的保护作用[J]. 中国中药杂志, 2018, 43(6):1241-1246. |
[23] |
ZHU Y H, XIAN X M, WANG Z Z, et al. Research progress on the relationship between atherosclerosis and inflammation[J]. Biomolecules,2018,8(3):80. doi: 10.3390/biom8030080 |
[24] |
肖安华, 李虹维, 颜春鲁, 等. 中药复方与有效成分调控NF-kB/MAPKs/JNK信号通路介导炎症反应抗AS的研究进展[J]. 中医药学报, 2019, 47(6):109-114. |
[25] |
CHENG L, PAN G F, ZHANG X D, et al. Yindanxinnaotong, a Chinese compound medicine, synergistically attenuates atherosclerosis progress[J]. Sci Rep,2015,5:12333. doi: 10.1038/srep12333 |
[26] |
刘叙阳, 姜华. 3种不同治法的中药复方对Toll样受体4及下游信号转导通路主要元件的影响[J]. 中国实验方剂学杂志, 2016, 22(1):121-124. |
[27] |
罗永苗. 基于NF-κB信号通路探讨参七脉心通胶囊抗动脉粥样硬化的作用机制[D]. 广州: 广州中医药大学, 2018. |
[28] |
张冰冰, 石岩, 朱爱松. 中药复方益糖康对动脉粥样硬化兔核因子KB和丝裂原活化蛋白激酶信号通路的影响[J]. 时珍国医国药, 2018, 29(1):56-58. |
[29] |
COLIN S, CHINETTI-GBAGUIDI G, STAELS B. Macrophage phenotypes in atherosclerosis[J]. Immunol Rev,2014,262(1):153-166. doi: 10.1111/imr.12218 |
[30] |
DALL'ASTA M, DERLINDATI E, ARDIGÒ D, et al. Macrophage polarization: the answer to the diet/inflammation conundrum? Nutr Metab Cardiovasc Dis,2012,22(5):387-392. doi: 10.1016/j.numecd.2011.12.010 |
[31] |
秦合伟, 李彦杰, 任锟, 等. 基于TLR3/TLR9介导巨噬细胞自噬/极化效应探讨血管软化丸抗AS的作用机制[J]. 辽宁中医杂志, 2019, 46(1):156-160, 225. |
[32] |
LI H R, CHANG L P, LIU Y J, et al. Effect of Tongxinluo on polarization of macrophages[J]. Chinese Pharmacological Bulletin,2017,33(4):577-580. |
[33] |
GUARNER F, MALAGELADA J R. Gut flora in health and disease[J]. Lancet,2003,361(9356):512-519. doi: 10.1016/S0140-6736(03)12489-0 |
[34] |
MENNI C, LIN C, CECELJA M, et al. Gut microbial diversity is associated with lower arterial stiffness in women[J]. Eur Heart J,2018,39(25):2390-2397. doi: 10.1093/eurheartj/ehy226 |
[35] |
LI J, LIN S Q, VANHOUTTE P M, et al. Akkermansia muciniphila protects against atherosclerosis by preventing metabolic endotoxemia-induced inflammation in apoe-/- mice[J]. Circulation,2016,133(24):2434-2446. doi: 10.1161/CIRCULATIONAHA.115.019645 |
[36] |
PIECZYNSKA M D, YANG Y, PETRYKOWSKI S, et al. Gut microbiota and its metabolites in atherosclerosis develop-ment[J]. Molecules,2020,25(3):594. doi: 10.3390/molecules25030594 |
[37] |
CHEN Y, XU C, HUANG R, et al. Butyrate from pectin fermentation inhibits intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E-deficient mice[J]. J Nutr Biochem,2018,56:175-182. doi: 10.1016/j.jnutbio.2018.02.011 |
[38] |
BARTOLOMAEUS H, BALOGH A, YAKOUB M, et al. Short-chain fatty acid propionate protects from hypertensive cardiovascular damage[J]. Circulation,2019,139(11):1407-1421. doi: 10.1161/CIRCULATIONAHA.118.036652 |
[39] |
ZHANG Y X, GU Y Y, CHEN Y H, et al. Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-α/SREBP1 pathway and modulating the gut microbiota in ApoE-/- mice fed with HFD[J]. J Ethnopharmacol,2021,266:113436. doi: 10.1016/j.jep.2020.113436 |
[40] |
ZHU B, ZHAI Y, JI M, et al. Alisma orientalis beverage treats atherosclerosis by regulating gut microbiota in ApoE-/- mice[J]. Front Pharmacol,2020,11:570555. doi: 10.3389/fphar.2020.570555 |
[41] |
JI W Y, JIANG T, SUN Z, et al. The enhanced pharmacological effects of modified traditional Chinese medicine in attenuation of atherosclerosis is driven by modulation of gut microbiota[J]. Front Pharmacol,2020,11:546589. doi: 10.3389/fphar.2020.546589 |
[42] |
SUBRAMANIAN S, BLANTON L V, FRESE S A, et al. Cultivating healthy growth and nutrition through the gut microbiota[J]. Cell,2015,161(1):36-48. doi: 10.1016/j.cell.2015.03.013 |
[43] |
CHEN P B, BLACK A S, SOBEL A L, et al. Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis[J]. Nat Biotechnol,2020,38(11):1288-1297. doi: 10.1038/s41587-020-0549-5 |