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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

两面针碱全合成及活性研究进展

赵增 陈浩 杨鸟 孙青龑 柳润辉

赵增, 陈浩, 杨鸟, 孙青龑, 柳润辉. 两面针碱全合成及活性研究进展[J]. 药学实践与服务, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
引用本文: 赵增, 陈浩, 杨鸟, 孙青龑, 柳润辉. 两面针碱全合成及活性研究进展[J]. 药学实践与服务, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
ZHAO Zeng, CHEN Hao, YANG Niao, SUN Qingyan, LIU Runhui. Research progress on total synthesis and activity of nitidine[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
Citation: ZHAO Zeng, CHEN Hao, YANG Niao, SUN Qingyan, LIU Runhui. Research progress on total synthesis and activity of nitidine[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002

两面针碱全合成及活性研究进展

doi: 10.3969/j.issn.1006-0111.2017.02.002

Research progress on total synthesis and activity of nitidine

  • 摘要: 两面针碱是传统中药两面针根的提取物,属于苯并菲啶类生物碱。研究发现两面针碱具有多种生物活性,对肿瘤、疟疾等多种疾病有效。笔者对两面针碱全合成方法及近年来的活性研究进行综述。
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    [16] Wang Z, Jiang W, Zhang Z, et al. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells[J]. J Ethnopharmacol, 2012, 144(1):145-150.
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    [20] Zhai H, Hu S, Liu T, et al. Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by suppressing the ERK signaling pathway[J]. Mol Med Rep, 2016, 13(3):2536-2542.
    [21] Jullian V, Bourdy G, Georges S, et al. Validation of use of a traditional antimalarial remedy from French Guiana, Zanthoxylum rhoifolium Lam[J]. J Ethnopharmacol, 2006, 106(3):348-352.
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两面针碱全合成及活性研究进展

doi: 10.3969/j.issn.1006-0111.2017.02.002

摘要: 两面针碱是传统中药两面针根的提取物,属于苯并菲啶类生物碱。研究发现两面针碱具有多种生物活性,对肿瘤、疟疾等多种疾病有效。笔者对两面针碱全合成方法及近年来的活性研究进行综述。

English Abstract

赵增, 陈浩, 杨鸟, 孙青龑, 柳润辉. 两面针碱全合成及活性研究进展[J]. 药学实践与服务, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
引用本文: 赵增, 陈浩, 杨鸟, 孙青龑, 柳润辉. 两面针碱全合成及活性研究进展[J]. 药学实践与服务, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
ZHAO Zeng, CHEN Hao, YANG Niao, SUN Qingyan, LIU Runhui. Research progress on total synthesis and activity of nitidine[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
Citation: ZHAO Zeng, CHEN Hao, YANG Niao, SUN Qingyan, LIU Runhui. Research progress on total synthesis and activity of nitidine[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 102-107,149. doi: 10.3969/j.issn.1006-0111.2017.02.002
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