| [1] | BANERJEE K, RESAT H. Constitutive activation of STAT3 in breast cancer cells: a review[J]. Int J Cancer,2016,138(11):2570-2578. doi: 10.1002/ijc.29923 |
| [2] | QIN J J, YAN L, ZHANG J, et al. STAT3 as a potential therapeutic target in triple negative breast cancer: a systematic review[J]. J Exp Clin Cancer Res,2019,38(1):195. doi: 10.1186/s13046-019-1206-z |
| [3] | 孙思博, 金时代, 郭人花. STAT3在非小细胞肺癌耐药中的研究进展[J]. 中国肺癌杂志, 2019, 22(7):457-463. doi: 10.3779/j.issn.1009-3419.2019.07.08 |
| [4] | ZHANG W D, YU W Y, CAI G P, et al. A new synthetic derivative of cryptotanshinone KYZ3 as STAT3 inhibitor for triple-negative breast cancer therapy[J]. Cell Death Dis,2018,9(11):1098. doi: 10.1038/s41419-018-1139-z |
| [5] | 王雨辰, 陈越, 季鸣, 等. STAT3靶点抑制剂Bt354抗前列腺癌作用及其分子机制研究[J]. 药学学报, 2019, 54(10):1851-1857. |
| [6] | XU L Y, SHI L X, QIU S S, et al. Design, synthesis, and evaluation of cyanopyridines as anti-colorectal cancer agents via inhibiting STAT3 pathway[J]. Drug Des Devel Ther,2019,13:3369-3381. doi: 10.2147/DDDT.S217800 |
| [7] | DAI X X, YIN C T, ZHANG Y, et al. Osthole inhibits triple negative breast cancer cells by suppressing STAT3[J]. J Exp Clin Cancer Res,2018,37(1):322. doi: 10.1186/s13046-018-0992-z |
| [8] | MCHUGH J. Systemic sclerosis: STAT3 - A key integrator of profibrotic signalling[J]. Nat Rev Rheumatol,2017,13(12):693. doi: 10.1038/nrrheum.2017.190 |
| [9] | LIU L, LIU F B, HUANG M, et al. Circular RNA ciRS-7 promotes the proliferation and metastasis of pancreatic cancer by regulating miR-7-mediated EGFR/STAT3 signaling pathway[J]. HBPD INT,2019,18(6):580-586. |
| [10] | YU H, LEE H, HERRMANN A, et al. Revisiting STAT3 signalling in cancer: new and unexpected biological functions[J]. Nat Rev Cancer,2014,14(11):736-746. doi: 10.1038/nrc3818 |
| [11] | CHEN Q, LV J, YANG W W, et al. Targeted inhibition of STAT3 as a potential treatment strategy for atherosclerosis[J]. Theranostics,2019,9(22):6424-6442. doi: 10.7150/thno.35528 |
| [12] | TURKSON J, RYAN D, KIM J S, et al. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation[J]. J Biol Chem,2001,276(48):45443-45455. doi: 10.1074/jbc.M107527200 |
| [13] | TIMOFEEVA O A, TARASOVA N I, ZHANG X P, et al. STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain[J]. Proc Natl Acad Sci USA,2013,110(4):1267-1272. doi: 10.1073/pnas.1211805110 |
| [14] | HUANG M, SONG K, LIU X Y, et al. AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses[J]. Nucleic Acids Res,2018,46(W1):W451-W458. doi: 10.1093/nar/gky374 |
| [15] | HUANG W, DONG Z Z, WANG F, et al. A small molecule compound targeting STAT3 DNA-binding domain inhibits cancer cell proliferation, migration, and invasion[J]. ACS Chem Biol,2014,9(5):1188-1196. doi: 10.1021/cb500071v |
| [16] | BUETTNER R, CORZANO R, RASHID R, et al. Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development[J]. ACS Chem Biol,2011,6(5):432-443. doi: 10.1021/cb100253e |
| [17] | CHENG X, LIU Y Q, WANG G Z, et al. Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor[J]. Oncotarget,2017,8(2):2681-2693. doi: 10.18632/oncotarget.13153 |
| [18] | SCHUST J, SPERL B, HOLLIS A, et al. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization[J]. Chem Biol,2006,13(11):1235-1242. doi: 10.1016/j.chembiol.2006.09.018 |
| [19] | CHEN H J, YANG Z D, DING C Y, et al. Discovery of O-alkylamino tethered niclosamide derivatives as potent and orally bioavailable anticancer agents[J]. ACS Med Chem Lett,2013,4(2):180-185. doi: 10.1021/ml3003082 |
| [20] | SHIN D S, KIM H N, SHIN K D, et al. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells[J]. Cancer Res,2009,69(1):193-202. doi: 10.1158/0008-5472.CAN-08-2575 |
| [21] | IWAMOTO K, UEHARA Y, INOUE Y, et al. Inhibition of STAT3 by anticancer drug bendamustine[J]. PLoS One,2017,12(1):e0170709. doi: 10.1371/journal.pone.0170709 |
| [22] | CHANG Y F, LIM K H, CHIANG Y W, et al. STAT3 induces G9a to exacerbate HER3 expression for the survival of epidermal growth factor receptor-tyrosine kinase inhibitors in lung cancers[J]. BMC Cancer,2019,19(1):959. doi: 10.1186/s12885-019-6217-9 |
| [23] | SHASTRI A, CHOUDHARY G, TEIXEIRA M, et al. Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells[J]. J Clin Invest,2018,128(12):5479-5488. doi: 10.1172/JCI120156 |