[1] YANG C F, QIAN R, XU Y, et al. Marine actinomycetes-derived natural products[J]. Curr Top Med Chem,2019,19(31):2868-2918.
[2] FENICAL W, JENSEN P R. Developing a new resource for drug discovery: marine actinomycete bacteria[J]. Nat Chem Biol,2006,2(12):666-673. doi:  10.1038/nchembio841
[3] BLUNT J W, CARROLL A R, COPP B R, et al. Marine natural products[J]. Nat Prod Rep,2018,35(1):8-53. doi:  10.1039/C7NP00052A
[4] THOMAS T, MOITINHO-SILVA L, LURGI M, et al. Diversity, structure and convergent evolution of the global sponge microbiome[J]. Nat Commun,2016,7:11870. doi:  10.1038/ncomms11870
[5] MORI T, CAHN J K B, WILSON M C, et al. Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated <italic>Entotheonella</italic> sponge symbionts[J]. Proc Natl Acad Sci USA,2018,115(8):1718-1723. doi:  10.1073/pnas.1715496115
[6] TIANERO M D, BALAICH J N, DONIA M S. Localized production of defence chemicals by intracellular symbionts of <italic>Haliclona</italic> sponges[J]. Nat Microbiol,2019,4(7):1149-1159. doi:  10.1038/s41564-019-0415-8
[7] CHOSHI T, UCHIDA Y, KUBOTA Y, et al. Lipase-catalyzed asymmetric synthesis of desprenyl-carquinostatin A and descycloavandulyl-lavanduquinocin[J]. Chem Pharm Bull,2007,55(7):1060-1064. doi:  10.1248/cpb.55.1060
[8] Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard-eighth edition[M]. CLSI document M07-A8. Wayne, PA: Clinical and Laboratory Standards Insitute, 2009.
[9] FURUKAWA Y, SAWAMOTO A, YAMAOKA M, et al. Effects of carbazole derivatives on neurite outgrowth and hydrogen peroxide-induced cytotoxicity in Neuro2a cells[J]. Molecules,2019,24(7):E1366. doi:  10.3390/molecules24071366
[10] KOBAYASHI M, TOMITA T, SHIN-YA K, et al. An unprecedented cyclization mechanism in the biosynthesis of carbazole alkaloids in <italic>Streptomyces</italic>[J]. Angew Chem Int Ed Engl,2019,58(38):13349-13353. doi:  10.1002/anie.201906864
[11] GUTIÉRREZ M, CAPSON T L, GUZMÁN H M, et al. Antiplasmodial metabolites isolated from the marine octocoral Muricea austera[J]. J Nat Prod,2006,69(10):1379-1383. doi:  10.1021/np060007f
[12] 陈明华, 巫晔翔, 董飚, 等. 链霉菌CPCC 202950的化学成分研究[J]. 中国中药杂志, 2015, 40(7):1320-1324.
[13]

SOLEDADE M, PEDRAS C, MORALES V M, et al. Phomapyrones: Three metabolites from the blackleg fungus[J]. Phytochemistry,1994,36(5):1315-1318. doi:  10.1016/S0031-9422(00)89658-2
[14] 王聪, 王立平, 范杰, 等. 深海链霉菌<italic>Streptomyces malaysiensis</italic> OUCMDZ-2167来源的细胞毒性产物[J]. 有机化学, 2017, 37(3):658-666.
[15]

MA M, RATEB M E, YANG D, et al. Germicidins H-J from <italic>Streptomyces sp</italic>. CB00361[J]. J Antibiot,2017,70(2):200-203. doi:  10.1038/ja.2016.100
[16]

BUTLER M S, ROBERTSON A A B, COOPER M A. Natural product and natural product derived drugs in clinical trials[J]. Nat Prod Rep,2014,31(11):1612-1661. doi:  10.1039/C4NP00064A
[17]

SCHMIDT A W, REDDY K R, KNÖLKER H J. Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids[J]. Chem Rev,2012,112(6):3193-3328. doi:  10.1021/cr200447s
[18]

KNÖLKER H J, REDDY K R. Isolation and synthesis of biologically active carbazole alkaloids[J]. Chem Rev,2002,102(11):4303-4427. doi:  10.1021/cr020059j
[19]

KATO S, SHINDO K, KATAOKA Y, et al. Studies on free radical scavenging substances from microorganisms. Ⅱ. Neocarazostatins A, B and C, novel free radical scavengers[J]. J Antibiot,1991,44(8):903-907. doi:  10.7164/antibiotics.44.903
[20]

SHIN-YA K, KUNIGAMI T, KIM J S, et al. Carquinostatin B, a new neuronal cell-protecting substance produced by <italic>Streptomyces exfoliatus</italic>[J]. Biosci Biotechnol Biochem,1997,61(10):1768-1769. doi:  10.1271/bbb.61.1768
[21]

SOBOLEVSKAYA M P, DENISENKO V A, MOISEENKO A S, et al. Bioactive metabolites of the marine actinobacterium <italic>Streptomyces sp</italic>. KMM 7210[J]. Russ Chem Bull,2007,56(4):838-840. doi:  10.1007/s11172-007-0126-9
[22] 何其伟, 刘吉开, 杜子伟, 等. 齿贝栓菌的化学成分[J]. 安徽中医学院学报, 2011, 30(2):73-76.
[23]

HEIDARI B, MOHAMMADIPANAH F. Isolation and identification of two alkaloid structures with radical scavenging activity from <italic>Actinokineospora sp</italic>. UTMC 968, a new promising source of alkaloid compounds[J]. Mol Biol Rep,2018,45(6):2325-2332. doi:  10.1007/s11033-018-4395-1
[24]

PETERSEN F, ZÄHNER H, METZGER J W, et al. Germicidin, an autoregulative germination inhibitor of <italic>Streptomyces viridochromogenes</italic> NRRL B-1551[J]. J Antibiot,1993,46(7):1126-1138. doi:  10.7164/antibiotics.46.1126