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Volume 31 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2013  >  31(3): 169-172,180

HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
Citation: HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
shu

Applied research of polyvinyl alcohol derivatives as hydrogel materials

doi: 10.3969/j.issn.1006-0111.2013.03.002

  • Anhui University of Traditional Chinese Medicine, Hefei 230031, China

  • Received Date: 2012-09-17
  • Rev Recd Date: 2013-01-25
  • Objective To introduce the application research progress of PVA derivatives as hydrogel materials, and provide the basis and reference for further development. Methods The related documents at home and abroad in recent years were integrated, analyzed and summarized. Results PVA derivatives as conventional and sensitive hydrogel materials were widely used in the fields of biomedicine, having a hydrophilic, softness, mild characteristics and good biocompatibility. Conclusion PVA is an excellent pharmaceutical excipient for potential re-development, and having a great value.
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    [2] Singh B,Sharma V.Design of psyllium-PVA-acrylic acid based novel hydrogels for use in antibiotic drug delivery[J].Int J Pharm,2010,389:94.
    [3] AL-Sabagh AM, Abdeen Z. Preparation and characterization of hydrogel based on PVA cross-linked by different cross-linkers used to dry organic solvents[J]. J Polym Environ,2010,18:576.
    [4] Otsuka E, Sugiyama M, Suzuki A. Formation and destruction of physical crosslinks by mild treatments in chemically crosslinked PVA gels[J].Polym Bull,2010,10:1007.
    [5] Wang JQ, Satoh M. Water properties in a novel thermoswelling PVA derivative hydrogel as studied by NMR and FTIR[J]. Langmuir, 2010, 26(16):13607.
    [6] Padavan DT,Hamilton AM,Millon LE,et al.Synthesis, characterization and in vitro cell compatibility study of a PAA graft/cross-linked PVA hydrogel[J]. ActaBiomaterialia,2011,7:258.
    [7] Alves MH,Young CJ,Bozzetto K,et al.Degradable,click PVA hydrogels:characterization of degradation and cellular compatibility[J]. Biomed Mater,2011,7:1.
    [8] Artyukhov AA,Shtilman MI,Kuskov AN,et al.Macroporous polymeric hydrogels formed from acrylate modified PVA macromers[J].Eur Polym J,2011,10(18):667.
    [9] Pan YS,Xiong DS,Gao F.Viscoelastic behavior of no-HA reinforced PVA gel biocomposites as an articular cartilage[J].J Mater Sci,2008,19:1963.
    [10] Cho SH,Lim SM,Han DK,et al.Time-dependent alginate/PVA hydrogels as injectable cell carriers[J].JBiomat Sci-Polym E,2009,20:863.
    [11] Negishi J,Nam KW,Kimura TS,et al.High-hydrostatic pressure technique is an effective method for the preparation of PVA-heparin hybridgel[J].Eur J Pharm Sci,2010,41:617.
    [12] Zan XJ,Kozlov M,McCarthy TJ,et al.Covalently attached, silver-doped PVA hydrogel films on Poly(L-lactic acid)[J].Biomacromolecules,2010,11:1082.
    [13] Abitbol T,Johnstone T,Quinn TM,et al.Reinforcement with cellulose nanocrystals of PVA hydrogels prepared by cyclic freezing and thawing[J].Soft Matter,2011,7:2373.
    [14] Bakhshandeh H,Soleimani M,Hosseini SS,et al.Poly (ε-caprolactone) nanofibrous ring surrounding a PVA hydrogel for the development of a biocompatible two-part artificial cornea[J].Int J Nanomed,2011,6:1509.
    [15] Sukhanova TV,Artyukhov AA,Prudchenko IA,et al.Entrapment and in vitro release of delta-sleep inducing peptide from polymer hydrogels based on modified PVA[J]. Biomedical Chemistry, 2012, 6(2):149.
    [16] 姚女兆.果胶/PVA复合水凝胶人工髓核的实验研究[D].南方医科大学,2010.
    [17] Aboutaleb MF,Ismail SA,El-kelesh NA.Radiation synthesis and characterization of PVA/MAA-GEL hydrogel for vitro drug delivery[J].J Macromol Sci B,2009,46:170.
    [18] Wang B,Liu MZ,Chen ZB,et al.Preparation, characterization and controlled release investigation of interpenetrating polymer networks of PAA/triazole modified PVA[J].Int J Pharm,2007,331:19.
    [19] 祝宝东,孟静,王鉴,等. PVA/淀粉接枝P(AA-AM)互穿网络水凝胶的合成与性能研究[J].科学技术与工程, 2011, 11(10):2234.
    [20] Qi BW,Yu AX,Zhu SB,et al.The preparation and cytocompatibility of injectable thermosensitive CS/PVA hydrogel[J].Med Sci,2010,30(1):89.
    [21] Tang YF,Du YM,Li Y,et al.A thermosensitive CS/PVA hydrogel containing hydroxyapatite for protein delivery[J].J Biomed Mater Res A, 2009, 91(4):953.
    [22] 陈丽如. CS/PVA温敏性水凝胶给药系统的研究[D].河北大学,2011.
    [23] 史林峰.PVA/AM接枝共聚物水凝胶的制备及表征[J].中国组织工程研究,2012,16(21):3919.
    [24] Zhang NY,Shen YG,Li XQ,et al.Synthesis and characterization of thermoand pH-sensitive PVA/poly(N,N-diethylacrylamide-co-itaconic acid) semi-IPN hydrogels[J].Biomed Mater,2012,7:1.
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Applied research of polyvinyl alcohol derivatives as hydrogel materials

doi: 10.3969/j.issn.1006-0111.2013.03.002
  • Anhui University of Traditional Chinese Medicine, Hefei 230031, China
  • Received Date: 2012-09-17
  • Rev Recd Date: 2013-01-25

Abstract: Objective To introduce the application research progress of PVA derivatives as hydrogel materials, and provide the basis and reference for further development. Methods The related documents at home and abroad in recent years were integrated, analyzed and summarized. Results PVA derivatives as conventional and sensitive hydrogel materials were widely used in the fields of biomedicine, having a hydrophilic, softness, mild characteristics and good biocompatibility. Conclusion PVA is an excellent pharmaceutical excipient for potential re-development, and having a great value.

HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
Citation: HU Xiao, HU Rong-feng, BAI Zhong-wen. Applied research of polyvinyl alcohol derivatives as hydrogel materials[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 169-172,180. doi: 10.3969/j.issn.1006-0111.2013.03.002
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