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ZHANG Wei, WEI Yan, MA Shoujiang. Re-evaluation on preparation technology of compound Chuanxiong dropping pills[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 60-62. doi: 10.3969/j.issn.1006-0111.2015.01.016
Citation: ZHANG Wei, WEI Yan, MA Shoujiang. Re-evaluation on preparation technology of compound Chuanxiong dropping pills[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 60-62. doi: 10.3969/j.issn.1006-0111.2015.01.016

Re-evaluation on preparation technology of compound Chuanxiong dropping pills

doi: 10.3969/j.issn.1006-0111.2015.01.016
  • Received Date: 2013-09-12
  • Rev Recd Date: 2014-02-25
  • Objective To optimize the preparation technology of compound Chuanxiong dropping pills. Methods Ratio of intermediate material to matrix,dripping temperature and condensate temperature were used as factors,with spherical degree,pill weight variatcon,dissolve time limit coefficient and appearance quality as indexes,the forming technology of compound Chuanxiong dropping pill was optimized by orthogonal test.The dropping preparation technology was optimized using dropping distance,dropping speed as factors. Results The optimal preparation conditions were as follows:ratio of intermediate material to matrix was 1:2,dropping temperature was 80℃,temperature of condensate was 15-20℃,dropping distance was 5 cm,dropping speed was 40 drops/min. Conclusion The preparation technology was reasonable,simple and easy to control for the preparation of compound Chuanxiong dropping pills.
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    [4] 夏 泉,张 平,李绍平,等.当归的药理作用研究进展[J].时珍国医国药,2004,15(3):164-166.
    [5] 周文孝.聚乙二醇在剂型优化中的应用[J].中国药学杂志,1995,30(12):713-716.
    [6] 栾立标,朱家壁.布洛芬滴丸剂的研制及体外溶出度[J].中国医药工业杂志,2000,31(9):359-402.
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Re-evaluation on preparation technology of compound Chuanxiong dropping pills

doi: 10.3969/j.issn.1006-0111.2015.01.016

Abstract: Objective To optimize the preparation technology of compound Chuanxiong dropping pills. Methods Ratio of intermediate material to matrix,dripping temperature and condensate temperature were used as factors,with spherical degree,pill weight variatcon,dissolve time limit coefficient and appearance quality as indexes,the forming technology of compound Chuanxiong dropping pill was optimized by orthogonal test.The dropping preparation technology was optimized using dropping distance,dropping speed as factors. Results The optimal preparation conditions were as follows:ratio of intermediate material to matrix was 1:2,dropping temperature was 80℃,temperature of condensate was 15-20℃,dropping distance was 5 cm,dropping speed was 40 drops/min. Conclusion The preparation technology was reasonable,simple and easy to control for the preparation of compound Chuanxiong dropping pills.

ZHANG Wei, WEI Yan, MA Shoujiang. Re-evaluation on preparation technology of compound Chuanxiong dropping pills[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 60-62. doi: 10.3969/j.issn.1006-0111.2015.01.016
Citation: ZHANG Wei, WEI Yan, MA Shoujiang. Re-evaluation on preparation technology of compound Chuanxiong dropping pills[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 60-62. doi: 10.3969/j.issn.1006-0111.2015.01.016
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