FAN Rong, REN Tianshu, ZHAO Qingchun, SHI Guobing. Meta-analysis on clinical study of western routine treatments combined with Tongxinluo capsule in treatment of angina pectoris[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 83-87. doi: 10.3969/j.issn.1006-0111.2015.01.024
| Citation:
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FAN Rong, REN Tianshu, ZHAO Qingchun, SHI Guobing. Meta-analysis on clinical study of western routine treatments combined with Tongxinluo capsule in treatment of angina pectoris[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 83-87. doi: 10.3969/j.issn.1006-0111.2015.01.024
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Meta-analysis on clinical study of western routine treatments combined with Tongxinluo capsule in treatment of angina pectoris
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Department of Pharmacy, General Hospital, Shenyang Military Region, Shenyang 100840, China
- Received Date: 2013-02-06
- Rev Recd Date:
2013-11-07
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Abstract
Objective To assess the effectiveness of western routine treatments combined with Tongxinluo capsule for angina pectoris. Methods The randomized controlled trials(RCTs) of western routine treatments combined with tongxinluo capsule for angina pectoris were collected through searching on computer from the following databases,CNKI(2000-2011),WanFang Data(2000-2011),WeiPu Data(2000-2011),PubMed(2000-2011) and manual search relevant journals,conference papers. Results A total of 11 studies were included and improvement rate of abnormal ECG were estimated in 9 studies and improvement rate of symptoms of angina were estimated in 11 studies.ECG clinical evaluation of the treatment group relative to the control group,relative risk (RR) value was 1.40 (95% CI:1.28-1.54),P<0.01,symptoms of angina clinical evaluation,treatment group relative to the control group RR value of 1.25 (95% CI:1.18-1.32),P<0.01.Only slight gastrointestinal discomfort were found in treatment group. Conclusion Tongxinluo capsule in combination on the basis of conventional western treatment could effectively improve the clinical efficacy and drug safety.
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