ZHANG Lulu, MIAO Qi, YE Zhaojiao, LI Hongjiao, JIANG Yuanying, CAO Yongbing. Fungistasis of nanometer silvers synthesized by different methods on Candida albicans[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 328-330,358. doi: 10.3969/j.issn.1006-0111.2015.04.010
| Citation:
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ZHANG Lulu, MIAO Qi, YE Zhaojiao, LI Hongjiao, JIANG Yuanying, CAO Yongbing. Fungistasis of nanometer silvers synthesized by different methods on Candida albicans[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 328-330,358. doi: 10.3969/j.issn.1006-0111.2015.04.010
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Fungistasis of nanometer silvers synthesized by different methods on Candida albicans
- 1.
School of Pharmacy, Second Military Medical University, Shanghai 200433, China
- 2.
School of Pharmacy, FuJian University of Traditional Chinese Medicine, Fuzhou 350108, China
- 3.
Department of Stomatology, Changhai Hospital Affliated to Second Military Medical University, Shanghai 200433, China
- Received Date: 2014-03-11
- Rev Recd Date:
2015-01-14
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Abstract
Objective To explore the in vitro fungistasis of nanometer silvers made by different methods on Candida albicans. Methods The minimal inhibitory concentrations (MICs) of Candida albicans strains stimulated to silver nanoparticles were determined by microdilution method.The combination effects of silver nanoparticles with fluconazole were determined by chess board check assay. Results The inhabitation effect of two kinds of silver nanoparticles were different on the growth of Candida albicans.Silver nanoparticles had a synergistic effect with fluconazole on Candida albicans. Conclusion The two kinds of silver nanoparticles had various antifungal activities in vitro and had a synergistic effect with fluconazole on Candida albicans.
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