Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema

LIN Xiuli; SHI Hekun; CHEN Shangyu; CHEN Jinshan

doi:10.3969/j.issn.1006-0111.2015.04.024

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Objective To assess the effects of compound glycyrrhizin tablets for chronic eczema patients using the Meta-analysis method. Methods The national literatures related to random control clinical trials on compound glycyrrhizin tablets for treating chronic eczema were retrieved. The method recommend by the cochrane collaboration to perform a Meta-analysis of randomized controlled trail(RCT)in RevMan 5.0 was applied. Results Nine articles were included, eight hundred and thirty patients were enrolled, and there were four hundred and fifteen cases for both the treatment group and control group. The results showed that both curative effect and safety of the treatment group with compound glycyrrhizin were better than that of the control group. Conclusion Compound glycyrrhizin had certain curative effect in the treatment of chronic eczema. It was safe and with less adverse effect. However, it still needs more strict and multicentre randomized double-blind control trial to provide more effective and convinced evidence.

Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema

Department of Pharmacy, No. 175 Hospital of PLA, Zhangzhou 363000, China

Received Date: 2014-01-14

Rev Recd Date: 2014-07-02

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Abstract: Objective To assess the effects of compound glycyrrhizin tablets for chronic eczema patients using the Meta-analysis method. Methods The national literatures related to random control clinical trials on compound glycyrrhizin tablets for treating chronic eczema were retrieved. The method recommend by the cochrane collaboration to perform a Meta-analysis of randomized controlled trail(RCT)in RevMan 5.0 was applied. Results Nine articles were included, eight hundred and thirty patients were enrolled, and there were four hundred and fifteen cases for both the treatment group and control group. The results showed that both curative effect and safety of the treatment group with compound glycyrrhizin were better than that of the control group. Conclusion Compound glycyrrhizin had certain curative effect in the treatment of chronic eczema. It was safe and with less adverse effect. However, it still needs more strict and multicentre randomized double-blind control trial to provide more effective and convinced evidence.

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Reference (12)

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Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema

doi: 10.3969/j.issn.1006-0111.2015.04.024

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