Progress on physiological activities and synthetic methods of ebselen

LIU Xiaoying; SUN Yiming; ZHAO Yuting; WU Xiandong; MA Pengchengb; YANG Chaoa; ZHENG Canhuia

doi:10.3969/j.issn.1006-0111.2017.01.002

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Organoselenium compounds are bioactive substances with extensive physiological activities. As a representative compound, ebselen could be used as mimics of glutathione peroxidase, and in the treatment of many diseases, such as cardiovascular and cerebrovascular diseases, inflammation and noise-induced hearing loss. the research progress in physiological activities and synthetic methods of ebselen were reviewed in this paper.

Progress on physiological activities and synthetic methods of ebselen

1. School of Pharmacy, Second Military Medical University, Shanghai 200433, China

2. Cadet Brigade, Second Military Medical University, Shanghai 200433, China

Received Date: 2016-03-08

Rev Recd Date: 2016-06-20

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Abstract: Organoselenium compounds are bioactive substances with extensive physiological activities. As a representative compound, ebselen could be used as mimics of glutathione peroxidase, and in the treatment of many diseases, such as cardiovascular and cerebrovascular diseases, inflammation and noise-induced hearing loss. the research progress in physiological activities and synthetic methods of ebselen were reviewed in this paper.

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Progress on physiological activities and synthetic methods of ebselen

doi: 10.3969/j.issn.1006-0111.2017.01.002

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