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Volume 36 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2018  >  36(2): 186-188,191

XIN Rujuan, PAN Huijun, LI Ying, AN Duopeng, ZHU Quangang. 302 cases of adverse drug reaction reports[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 186-188,191. doi: 10.3969/j.issn.1006-0111.2018.02.020
Citation: XIN Rujuan, PAN Huijun, LI Ying, AN Duopeng, ZHU Quangang. 302 cases of adverse drug reaction reports[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 186-188,191. doi: 10.3969/j.issn.1006-0111.2018.02.020
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302 cases of adverse drug reaction reports

doi: 10.3969/j.issn.1006-0111.2018.02.020

  • Department of Pharmacy, Shanghai Dermatology Hospital, Shanghai 200443, China

  • Received Date: 2017-10-25
  • Rev Recd Date: 2017-12-29
  • Objective To study the features, general patterns and predisposing factors of adverse drug reactions (ADR) occurred in our hospital and to provide the guidance for rational and safe use of drugs in clinic. Methods 302 cases of ADR were reported from September 2015 to September 2017 in our hospital. Age distribution, gender, route of administration, drug categories, systems or organs involved, clinical manifestations, adverse reaction types involved in ADRs were analyzed retrospectively. Results Among the 302 ADR reports, 137 cases are male patients (accounting for 45.4%) and 165 cases were female patients (accounting for 54.6%). 27.8% of ADR was related to anti-infective agents. 70.2% of ADR came from oral administration and 24.8% ADR was due to intravenous administration. The main clinical manifestations of ADR were lesion of skin and its appendants (61.6%) and followed by the digestive system injury (15.9%). Conclusion The multiple factors may lead to high frequency of ADR. In order to promote rational drug use and reduce the occurrence of ADR, clinicians should pay attention to the ADR monitoring and strictly follow the clinical indications of medications.
  • [1] 陈新谦,金有豫,汤光.新编药物学[M].17版.北京:人民卫生出版社,2011.
    [2] 徐建东,沈敏,李莹,等. 某院160例药物不良反应报告分析[J]. 重庆医学,2012,41(14):1407-1408.
    [3] 朱曼,凡超,郭代红,等.军队医院1175例抗感染药物严重药品不良反应/事件报告分析[J].中国药物应用与监测,2015,12(3):163-167.
    [4] 蒋宇利,冯琳,欧宁,等.2002年我院药品不良反应报告分析[J].中国药房,2003, 14(10):614-616.
    [5] 吴迪,王真.某院2013-2015年813例ADR报告分析[J]. 中国药房,2017,28(17):2359-2362.
    [6] 赵启邹,王青,聂彩霞,等.大理市第一人民医院114例药品不良反应报告分析[J]. 中国医院用药评价与分析,2015,15(2):242-244.
    [7] 徐克明. 中药注射剂不良反应分析及合理应用[J]. 天津中医药,2016,33(7):411-443.
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302 cases of adverse drug reaction reports

doi: 10.3969/j.issn.1006-0111.2018.02.020
  • Department of Pharmacy, Shanghai Dermatology Hospital, Shanghai 200443, China
  • Received Date: 2017-10-25
  • Rev Recd Date: 2017-12-29

Abstract: Objective To study the features, general patterns and predisposing factors of adverse drug reactions (ADR) occurred in our hospital and to provide the guidance for rational and safe use of drugs in clinic. Methods 302 cases of ADR were reported from September 2015 to September 2017 in our hospital. Age distribution, gender, route of administration, drug categories, systems or organs involved, clinical manifestations, adverse reaction types involved in ADRs were analyzed retrospectively. Results Among the 302 ADR reports, 137 cases are male patients (accounting for 45.4%) and 165 cases were female patients (accounting for 54.6%). 27.8% of ADR was related to anti-infective agents. 70.2% of ADR came from oral administration and 24.8% ADR was due to intravenous administration. The main clinical manifestations of ADR were lesion of skin and its appendants (61.6%) and followed by the digestive system injury (15.9%). Conclusion The multiple factors may lead to high frequency of ADR. In order to promote rational drug use and reduce the occurrence of ADR, clinicians should pay attention to the ADR monitoring and strictly follow the clinical indications of medications.

XIN Rujuan, PAN Huijun, LI Ying, AN Duopeng, ZHU Quangang. 302 cases of adverse drug reaction reports[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 186-188,191. doi: 10.3969/j.issn.1006-0111.2018.02.020
Citation: XIN Rujuan, PAN Huijun, LI Ying, AN Duopeng, ZHU Quangang. 302 cases of adverse drug reaction reports[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 186-188,191. doi: 10.3969/j.issn.1006-0111.2018.02.020
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