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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2019  >  37(2): 97-102

ZHANG Yu, WANG Pengyuan, LIU Xia. Research progress on obesity type 2 diabetes mellitus drug[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 97-102. doi: 10.3969/j.issn.1006-0111.2019.02.001
Citation: ZHANG Yu, WANG Pengyuan, LIU Xia. Research progress on obesity type 2 diabetes mellitus drug[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 97-102. doi: 10.3969/j.issn.1006-0111.2019.02.001
shu

Research progress on obesity type 2 diabetes mellitus drug

doi: 10.3969/j.issn.1006-0111.2019.02.001

  • Department of Pharmacology, School of Pharmacy, Naval Medical University, Shanghai 200433, China

  • Received Date: 2018-09-05
  • Rev Recd Date: 2019-01-03
  • Obesity is closely relative to the increase in diabetes incidence. Most of the current hypoglycemic medicines,such as insulin and its analogues,insulin secretion enhancers,insulin sensitizers and so on,would lead to weight gain,thus aggravating insulin resistance and increasing the dosage of hypoglycemic drugs,which had formed a vicious circle. The development of new drugs targeting both reducing blood sugar and controlling weight had attracted much more attention. the epidemiology of obese type 2 diabetes mellitus and the effect of currently available hypoglycemic drugs on weight development had been reviewed in this article,and the latest targets of hypoglycemic medicines with weight loss effects were highlighted,in order to provide a potential approach for the treatment of obese type 2 diabetes mellitus.
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Research progress on obesity type 2 diabetes mellitus drug

doi: 10.3969/j.issn.1006-0111.2019.02.001
  • Department of Pharmacology, School of Pharmacy, Naval Medical University, Shanghai 200433, China
  • Received Date: 2018-09-05
  • Rev Recd Date: 2019-01-03

Abstract: Obesity is closely relative to the increase in diabetes incidence. Most of the current hypoglycemic medicines,such as insulin and its analogues,insulin secretion enhancers,insulin sensitizers and so on,would lead to weight gain,thus aggravating insulin resistance and increasing the dosage of hypoglycemic drugs,which had formed a vicious circle. The development of new drugs targeting both reducing blood sugar and controlling weight had attracted much more attention. the epidemiology of obese type 2 diabetes mellitus and the effect of currently available hypoglycemic drugs on weight development had been reviewed in this article,and the latest targets of hypoglycemic medicines with weight loss effects were highlighted,in order to provide a potential approach for the treatment of obese type 2 diabetes mellitus.

ZHANG Yu, WANG Pengyuan, LIU Xia. Research progress on obesity type 2 diabetes mellitus drug[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 97-102. doi: 10.3969/j.issn.1006-0111.2019.02.001
Citation: ZHANG Yu, WANG Pengyuan, LIU Xia. Research progress on obesity type 2 diabetes mellitus drug[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(2): 97-102. doi: 10.3969/j.issn.1006-0111.2019.02.001
shu

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