Liver damage caused by sodium valproate medication error: a case report

ZHOU Ting; CAI Jian; DUAN Jingjing; LIU Fenlian; HU Fangbao; LU Saihua

doi:10.3969/j.issn.1006-0111.2019.05.016

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Objective To analyze the participation effect of clinical pharmacist during the treatment process of sodium valproate in a patient with secondary epilepsy after stroke. Methods The correct dose and usage of sodium valproate under TDM,the most common ADR and the potential DI were introduced by clinical pharmacists who participated in the whole course treatment of sodium valproate. Results The convulsion was controlled and the liver damage caused by sodium valproate was recovered. Conclusion Clinical pharmacist should not only pay attention to ADRs under normal usage and dosage,but also pay special attention to the ability to deal with drug errors,so as to promote rational and individualized drug use.

Liver damage caused by sodium valproate medication error: a case report

1. Department of Pharmacy, Central Hospital of Fengxian District, Shanghai 201499, China

2. Department of Medical Affair, Mental Health Center of Fengxian District, Shanghai 201499, China

3. ICU, Central Hospital of Fengxian District, Shanghai 201499, China

Received Date: 2019-02-21

Rev Recd Date: 2019-05-22

Key words:

Abstract: Objective To analyze the participation effect of clinical pharmacist during the treatment process of sodium valproate in a patient with secondary epilepsy after stroke. Methods The correct dose and usage of sodium valproate under TDM,the most common ADR and the potential DI were introduced by clinical pharmacists who participated in the whole course treatment of sodium valproate. Results The convulsion was controlled and the liver damage caused by sodium valproate was recovered. Conclusion Clinical pharmacist should not only pay attention to ADRs under normal usage and dosage,but also pay special attention to the ability to deal with drug errors,so as to promote rational and individualized drug use.

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Reference (8)

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Liver damage caused by sodium valproate medication error: a case report

doi: 10.3969/j.issn.1006-0111.2019.05.016

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通讯作者: 陈斌, bchen63@163.com

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