Pharmacokinetic analysis and individual administration of cyclosporine for a juvenile renal transplant patients
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Key words:
- renal transplant /
- cyclosporine /
- pharmacokinetic analysis /
- individual administration
Abstract: It was reported that a juvenile renal transplant patients had a low cyclosporine whole blood concentration after normal administration.The pharmacokinetic parameters were: T1/2(Ke) = 3.15h, Tmax = 1.88h,Cmax=498.41ng·ml-1,AUC=3188.65(ng·ml-1)·h-1.Computer software was used to design the individual administration, that was 200mg, tid. Satisfactory effect was acquired.
Citation: | Zhang Xianjie, Ni Fuying, Lu Weiai. Pharmacokinetic analysis and individual administration of cyclosporine for a juvenile renal transplant patients[J]. Journal of Pharmaceutical Practice and Service, 1997, (3): 151-153. |