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Volume 16 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1998  >  (2): 84-86,107

Sun Chengchun, Jia Nuan, Wang Jingxiang. Dose-effect relationship and toxicity of Strychnos nux-vomica L[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 84-86,107.
Citation: Sun Chengchun, Jia Nuan, Wang Jingxiang. Dose-effect relationship and toxicity of Strychnos nux-vomica L[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 84-86,107.
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Dose-effect relationship and toxicity of Strychnos nux-vomica L

  • General Hospital of Jinan Military, Jinan 250031

  • It is evident that anti-inflammation and analgesia in dose-dependent of Strychnos nux-vomica L. from 40mg/kg to 80mg/kg, when the dose less than 40mg/kg it only showed anti-inflammation, its toxicity increased when more than 80mg/kg. Strychnos nux-vomica L. also might increase evidently the weight of thymus. The po LD50 in mice was 140.13±14.74mg/kg. The results suggested that the dose of Strychnos nux-vomica L. must be suitable.
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Dose-effect relationship and toxicity of Strychnos nux-vomica L

  • General Hospital of Jinan Military, Jinan 250031

Abstract: It is evident that anti-inflammation and analgesia in dose-dependent of Strychnos nux-vomica L. from 40mg/kg to 80mg/kg, when the dose less than 40mg/kg it only showed anti-inflammation, its toxicity increased when more than 80mg/kg. Strychnos nux-vomica L. also might increase evidently the weight of thymus. The po LD50 in mice was 140.13±14.74mg/kg. The results suggested that the dose of Strychnos nux-vomica L. must be suitable.

Sun Chengchun, Jia Nuan, Wang Jingxiang. Dose-effect relationship and toxicity of Strychnos nux-vomica L[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 84-86,107.
Citation: Sun Chengchun, Jia Nuan, Wang Jingxiang. Dose-effect relationship and toxicity of Strychnos nux-vomica L[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 84-86,107.
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