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Zhang Mingxiang, Zhang Li, Zhou Ring. Effect of strong light on the stability of ofloxacin and glucose injection[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 92-94.
Citation: Zhang Mingxiang, Zhang Li, Zhou Ring. Effect of strong light on the stability of ofloxacin and glucose injection[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 92-94.

Effect of strong light on the stability of ofloxacin and glucose injection

  • Effects of different pH, illumination time, illumination intensity on the stability of ofloxacin were observed by means of cross curve experiment design. The results showed that no significant change was found in the apperance of the solution, pH, A450nm, the antibacterial activity against escherichiacoli after illuminating. However the content of ofloxacin reduces and the area of impurity peak increases. The effect of pH on the stability of ofloxacin is greater than illumination time and illumination intensity.
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Effect of strong light on the stability of ofloxacin and glucose injection

Abstract: Effects of different pH, illumination time, illumination intensity on the stability of ofloxacin were observed by means of cross curve experiment design. The results showed that no significant change was found in the apperance of the solution, pH, A450nm, the antibacterial activity against escherichiacoli after illuminating. However the content of ofloxacin reduces and the area of impurity peak increases. The effect of pH on the stability of ofloxacin is greater than illumination time and illumination intensity.

Zhang Mingxiang, Zhang Li, Zhou Ring. Effect of strong light on the stability of ofloxacin and glucose injection[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 92-94.
Citation: Zhang Mingxiang, Zhang Li, Zhou Ring. Effect of strong light on the stability of ofloxacin and glucose injection[J]. Journal of Pharmaceutical Practice and Service, 1998, (2): 92-94.

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