Preparation and in vitro evaluation of ketoprofen gel for transdermal drug delivery

Hu Jinhong; Zhang Wanguo; Zheng Xiaomei

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Volume 17 Issue 1

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Article Navigation > Journal of Pharmaceutical Practice and Service > 1999 > (1): 27-28

Hu Jinhong, Zhang Wanguo, Zheng Xiaomei. Preparation and in vitro evaluation of ketoprofen gel for transdermal drug delivery[J]. Journal of Pharmaceutical Practice and Service, 1999, (1): 27-28.

Citation:

Hu Jinhong, Zhang Wanguo, Zheng Xiaomei. Preparation and in vitro evaluation of ketoprofen gel for transdermal drug delivery[J]. Journal of Pharmaceutical Practice and Service, 1999, (1): 27-28.

Preparation and in vitro evaluation of ketoprofen gel for transdermal drug delivery

Department of Pharmacy, Changhai Hospital, Shanghai 200433

Received Date: 1998-07-21

Abstract

OBJECTIVE To study the prepartion of ketoprofen gel and its in vitro release. METHODS PVA and glycerin was used as carriers. RESULTS KFP was delivered at zero order.The higher the drug content,the faster the delivery speed.5% urea had no effect on KFP transdermal delivery.At a content of more than 10%,urea could significantly accelerate KFP transdermal delivery. CONCLUSION Gel was stable and accorded the clinical demands.
- ketoprofen,
- polyvinyl alcohol,
- in vitro release,
- transdermal patch the clinical demands.
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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