Synthesis and antibacterial activity of 7-(pyridy1-N-oxide-2-thio)-1-(2-fluoroethy1)-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
- Received Date: 1998-12-21
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Key words:
- fluoroquinolone /
- synthesis /
- antibacterial activity
Abstract: OBJECTIVE To study on antibacterial activity of 7-(pyridy1-N-oxide-2-thio)-1-(2-fluoroethy1)-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid.METHODS Synthesis and determine antibacterial activity of the compound invitro.RUSULTS The compound exhibited definte antibacterial activity.CONCLUSION The compound showed better antibacterial activity.
Citation: | Yan Ligang, Wang Jie, Song Juzhong, Xie Huaijiang, Luo Na. Synthesis and antibacterial activity of 7-(pyridy1-N-oxide-2-thio)-1-(2-fluoroethy1)-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid[J]. Journal of Pharmaceutical Practice and Service, 1999, (4): 199-201. |