Study on the method of dissolution test of norfloxacin Capsule
- Received Date: 1999-03-10
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Key words:
- norfloxacin capsule /
- UV-Spectrophotometry /
- dissolution
Abstract: OBJECTIVE To study the condition and method using UV-spectrophotomery for determining the concentration and dissolution of Norfloxacin capsule.METHODS The concentration of Norfloxacin capsule was detected by UV-spectrophotometry and the dissolution was detected by rotation basket method.RESULTS The iggest absorbtion was at 273nm wavelength(5μg/ml,0.4% NaOH solution).The average absorption coefficient(E1cm1%)is 1095,And the linear relationship was good(r=0 9998)In 20minutes,the dissolution rates were 80%.CONCLUSION The concentration of Norfloxacin can be detected by UV-spectrophotometry,it′s convient and rapid.It can also be wsed to detect the dvssolution of Norfloxacin capsule.
Citation: | Wang Yanping, Liu Fuqiang, Wang Weidong, Liu Ge. Study on the method of dissolution test of norfloxacin Capsule[J]. Journal of Pharmaceutical Practice and Service, 1999, (4): 230-232. |