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Volume 17 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1999  >  (5): 298-299

Jing Li, Zeng Renjie, Sun Weizhang, Liu Qing. Study on the dissolution of mitoxantrone in mitoxantron-hydroxylapatite ceramic composites in vitro[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 298-299.
Citation: Jing Li, Zeng Renjie, Sun Weizhang, Liu Qing. Study on the dissolution of mitoxantrone in mitoxantron-hydroxylapatite ceramic composites in vitro[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 298-299.
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Study on the dissolution of mitoxantrone in mitoxantron-hydroxylapatite ceramic composites in vitro

  • 1.

    Department Pharmacy of Chengdu General Hospital of PLA, Chengdu 610083

  • 2.

  • Received Date: 1999-02-01
  • OBJECTIVE To investigate the drug-releasing regularity in vitro of variable concentration mitoxantrone,which wax in a matoxantrone hydroxylapatite ceramic composite encapsulated with wax (DHAQ-PHA-WAX) and DHAQ-PHA without the wax.hydroxylapatite ceramic was used as drug carrier and wax as inhibitor. METHODS The released drug concentration per-day was determined by visible spectrometry at λ =660nm. RESULTS There was a significant difference (P<0.05) between DHAQ-PHA dissolution velocity and DHAQ-PHA-WAX. CONCLUTION Releasing of DHAQ could be controlled with DHAQ-PHA-WAX.
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通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on the dissolution of mitoxantrone in mitoxantron-hydroxylapatite ceramic composites in vitro

  • 1. Department Pharmacy of Chengdu General Hospital of PLA, Chengdu 610083
  • 2. 
  • Received Date: 1999-02-01

Abstract: OBJECTIVE To investigate the drug-releasing regularity in vitro of variable concentration mitoxantrone,which wax in a matoxantrone hydroxylapatite ceramic composite encapsulated with wax (DHAQ-PHA-WAX) and DHAQ-PHA without the wax.hydroxylapatite ceramic was used as drug carrier and wax as inhibitor. METHODS The released drug concentration per-day was determined by visible spectrometry at λ =660nm. RESULTS There was a significant difference (P<0.05) between DHAQ-PHA dissolution velocity and DHAQ-PHA-WAX. CONCLUTION Releasing of DHAQ could be controlled with DHAQ-PHA-WAX.

Jing Li, Zeng Renjie, Sun Weizhang, Liu Qing. Study on the dissolution of mitoxantrone in mitoxantron-hydroxylapatite ceramic composites in vitro[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 298-299.
Citation: Jing Li, Zeng Renjie, Sun Weizhang, Liu Qing. Study on the dissolution of mitoxantrone in mitoxantron-hydroxylapatite ceramic composites in vitro[J]. Journal of Pharmaceutical Practice and Service, 1999, (5): 298-299.
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