Study on the dissolution of diflunisal capsules
- Received Date: 1999-04-19
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Key words:
- diflunisal /
- capsule /
- tablet /
- dissolution
Abstract: OBJECTIVE The vitro release of diflunisal capsules were compared with the tablets (imported,made by Merck Corporation). METHODS Referring to the USP ⅩⅩⅢ,the dissolution and the content of two kinds of dosage forms containing diflunisal were determined by UV spectropholometer respectively. RESULTS The average recovery was 100.27%(RSD =0.62%).The in vitro release of capsules was faster that of diflunisal material and available tablets. T80 of capsules was 12.8min vs.13.08min of tablets. CONCLUSION The rate of dissolution has no significance differences between the capsules and the imported tablets.
Citation: | Lin fang, Wang Shenghao, Wang Guoqiang, Han Jinwen. Study on the dissolution of diflunisal capsules[J]. Journal of Pharmaceutical Practice and Service, 1999, (6): 339-341. |