Synthesis technology of fleroxacin material for injection

Yan Ligang; Sun Hua; Song Juzhong; Xie Huaijiang

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Volume 17 Issue 6

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Article Navigation > Journal of Pharmaceutical Practice and Service > 1999 > (6): 349-351

Yan Ligang, Sun Hua, Song Juzhong, Xie Huaijiang. Synthesis technology of fleroxacin material for injection[J]. Journal of Pharmaceutical Practice and Service, 1999, (6): 349-351.

Citation:

Yan Ligang, Sun Hua, Song Juzhong, Xie Huaijiang. Synthesis technology of fleroxacin material for injection[J]. Journal of Pharmaceutical Practice and Service, 1999, (6): 349-351.

Synthesis technology of fleroxacin material for injection

Institute of Military Medicine, Shenyang Military District of PLA Shenyang 110031

Received Date: 1999-02-09

Abstract

OBJECTIVE To study the synthetic method and technology of fleroxacin material for injection. METHODS This compound was synthesized using 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-ethylcarbonate as material. RESULTS The element analysis,IR,MS and HNMR of synthetic product were comformable to literature,the total yield was 56.3%.The product was identified,its quality accords with injection′s demands. CONCLUSION Fleroxacin material of this technology synthesized accords with injection′s demands,and it can be used for injection′s production.
- fleroxacin,
- quinolone,
- synthesis technology
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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