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KANG Lian-chun, JIA Yi-xing, ZHOU Yong-shuang, ZHAO Xi-rong, GOU Ling, KANG Su-hai, WANG Qi-fu. Clinical observation of mannitol as pain-reliever for cancer pain[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 131-133.
Citation: KANG Lian-chun, JIA Yi-xing, ZHOU Yong-shuang, ZHAO Xi-rong, GOU Ling, KANG Su-hai, WANG Qi-fu. Clinical observation of mannitol as pain-reliever for cancer pain[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 131-133.

Clinical observation of mannitol as pain-reliever for cancer pain

  • Received Date: 1999-10-12
  • OBJECTIVE To study the effect of mannitol as pain-reliever for malignant tumor pain.METHODS 320 patients with malignant tumor pain,divided into once daily group and twice daily group,were given 20% mannitol 250ml by intravenous infusion.To compare the effect of relieve pain of mannitol,the malignant tumor patients treated with radiotherapy were divided into purely radiotherapy group and radiotherapy plus intravenous drip mannitol group.RESULTS The rates completely relieve about the two groups were 68.5% and 70.6%(P>0.05).The rates of 4,5 and 6 pain degree about purely radiotherapy were higher than that of radiotherapy plus mannitol group(12.5% and 0)(P<0.01).CONCLUSION Intravenous drip mannitol can prevent and kill the acute cancer pain and the pain results from radiotherapy.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Clinical observation of mannitol as pain-reliever for cancer pain

Abstract: OBJECTIVE To study the effect of mannitol as pain-reliever for malignant tumor pain.METHODS 320 patients with malignant tumor pain,divided into once daily group and twice daily group,were given 20% mannitol 250ml by intravenous infusion.To compare the effect of relieve pain of mannitol,the malignant tumor patients treated with radiotherapy were divided into purely radiotherapy group and radiotherapy plus intravenous drip mannitol group.RESULTS The rates completely relieve about the two groups were 68.5% and 70.6%(P>0.05).The rates of 4,5 and 6 pain degree about purely radiotherapy were higher than that of radiotherapy plus mannitol group(12.5% and 0)(P<0.01).CONCLUSION Intravenous drip mannitol can prevent and kill the acute cancer pain and the pain results from radiotherapy.

KANG Lian-chun, JIA Yi-xing, ZHOU Yong-shuang, ZHAO Xi-rong, GOU Ling, KANG Su-hai, WANG Qi-fu. Clinical observation of mannitol as pain-reliever for cancer pain[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 131-133.
Citation: KANG Lian-chun, JIA Yi-xing, ZHOU Yong-shuang, ZHAO Xi-rong, GOU Ling, KANG Su-hai, WANG Qi-fu. Clinical observation of mannitol as pain-reliever for cancer pain[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 131-133.

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