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ZHANG Hui, GU Ming-jun, LIU Zhi-min, Shi, Yong-quan. Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 134-136.
Citation: ZHANG Hui, GU Ming-jun, LIU Zhi-min, Shi, Yong-quan. Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 134-136.

Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone

  • Received Date: 1999-10-22
  • OBJECTIVE To investigate the efficacy and safety of topical intrathyroid injection of dexamethasone in the patients with subacute thyroiditis.METHODS Twenty patients with subacute thyroiditis were divided randomly into two groups.10 Patients (group A) were treated with topical intrathyroid injection of dexamethasone(5mg/ml,twice perweek),10 Patients (group B)were treated with prednisone 30 mg/d orally.Clinical outcomes of two groups are compared after 2 weeks,4 weeks and 8 weeks.RESULTS Curative rate of group A and group B after 8 weeks were 90% and 100% respectively and there were no significant difference(P>0.25).Duration of therapy were(5.6±2.1) weeks in group A and (8.2±1.8) weeks in group B respectively and there were significant difference (P<0.05).No adverse reactions occurred in both groups.CONCLUSIONS:Topical injection of dexamethasone in patients with subacute thyroiditis improves the symptoms rapidly and shorten the course of disease,so it is highly effective and safe.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone

Abstract: OBJECTIVE To investigate the efficacy and safety of topical intrathyroid injection of dexamethasone in the patients with subacute thyroiditis.METHODS Twenty patients with subacute thyroiditis were divided randomly into two groups.10 Patients (group A) were treated with topical intrathyroid injection of dexamethasone(5mg/ml,twice perweek),10 Patients (group B)were treated with prednisone 30 mg/d orally.Clinical outcomes of two groups are compared after 2 weeks,4 weeks and 8 weeks.RESULTS Curative rate of group A and group B after 8 weeks were 90% and 100% respectively and there were no significant difference(P>0.25).Duration of therapy were(5.6±2.1) weeks in group A and (8.2±1.8) weeks in group B respectively and there were significant difference (P<0.05).No adverse reactions occurred in both groups.CONCLUSIONS:Topical injection of dexamethasone in patients with subacute thyroiditis improves the symptoms rapidly and shorten the course of disease,so it is highly effective and safe.

ZHANG Hui, GU Ming-jun, LIU Zhi-min, Shi, Yong-quan. Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 134-136.
Citation: ZHANG Hui, GU Ming-jun, LIU Zhi-min, Shi, Yong-quan. Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 134-136.

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