Anti inflammatory action of cobra(Naja naja)venom
- Received Date: 2000-03-07
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Key words:
- cobra(Naja naja)venom /
- rat /
- rheumatoid arthritis
Abstract: ORJECTIVE:To observe the antiinflammatory action of cobra(Naja naja)venom.METHODS Cobra venom was administered subcutaneously at doses of 2μg/kg,10μg/kg and 50μg/kg for 20 days after Freund complete adjuvant infection and intragastrically at dose of 25mg/kg for 7 days after cotton pellets planted in rats.RESULTS Cobra venom had no effect on the edema induced by adjuvant,but inhibited markedly granuloma information caused by cotton pellets in rats.CONCLUSION Cobra venom may be effective on synovitis.
Citation: | ZHANG Li-ming, CHEN Zhi-long, ZHAO Jie, SUN Jie. Anti inflammatory action of cobra(Naja naja)venom[J]. Journal of Pharmaceutical Practice and Service, 2000, (4): 209-211. |