Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

XIANG Guang-ya, YANG Yu, RUAN Jin-lan, ZHOU Yi-kai. Studies of cytotoxic effect and antitumor effect by Hypericum chinense[J]. Journal of Pharmaceutical Practice and Service, 2001, (1): 16-18,64.
Citation: XIANG Guang-ya, YANG Yu, RUAN Jin-lan, ZHOU Yi-kai. Studies of cytotoxic effect and antitumor effect by Hypericum chinense[J]. Journal of Pharmaceutical Practice and Service, 2001, (1): 16-18,64.

Studies of cytotoxic effect and antitumor effect by Hypericum chinense

  • Received Date: 2000-06-27
  • OBJECTIVE To study the cytotoxic effect in vitro and antitumor effect in vivo of Hypericum chinense.METHODS MTT and SRB assay method in vitro and antitumor test in vivo were used.RESULTS The extracts F003、F004、F006 and the compounds hyperlacton C, quercetin, quercitrin show cytotoxic effect on different carcinoma cell in vitro; Under the dose of 20.0mg/(kg·d) × 10d, the inhibitory rates of F003、F004、F005 on S180 in mice were 20.7%、12.4%、31.4 %.CONCLUSION Hypericum chinense show cytotoxic effect in vitro and antitumor effect in viva and should he studied further.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(2614) PDF downloads(932) Cited by()

Related
Proportional views

Studies of cytotoxic effect and antitumor effect by Hypericum chinense

Abstract: OBJECTIVE To study the cytotoxic effect in vitro and antitumor effect in vivo of Hypericum chinense.METHODS MTT and SRB assay method in vitro and antitumor test in vivo were used.RESULTS The extracts F003、F004、F006 and the compounds hyperlacton C, quercetin, quercitrin show cytotoxic effect on different carcinoma cell in vitro; Under the dose of 20.0mg/(kg·d) × 10d, the inhibitory rates of F003、F004、F005 on S180 in mice were 20.7%、12.4%、31.4 %.CONCLUSION Hypericum chinense show cytotoxic effect in vitro and antitumor effect in viva and should he studied further.

XIANG Guang-ya, YANG Yu, RUAN Jin-lan, ZHOU Yi-kai. Studies of cytotoxic effect and antitumor effect by Hypericum chinense[J]. Journal of Pharmaceutical Practice and Service, 2001, (1): 16-18,64.
Citation: XIANG Guang-ya, YANG Yu, RUAN Jin-lan, ZHOU Yi-kai. Studies of cytotoxic effect and antitumor effect by Hypericum chinense[J]. Journal of Pharmaceutical Practice and Service, 2001, (1): 16-18,64.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return