The improve of the method for determination compound fluocinonide ointment
- Received Date: 2002-01-15
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Key words:
- compound fluocinonide /
- RP-HPLC /
- ointment
Abstract: OBJECTIVE To improve the method for determination compound fluocinonide ointment.METHODS A method of RP HPLC be used, plus the internal standard after extraction and filter.ODS column (250mm×4.6mm, 5μm) was selected and the mobile phase was consisted of methanol-water-ether(62:38:2,v/v/v) at flow rate of 1.0ml·min-1.The detection wavelength was 240nm.RESULTS The precision and the accuracy of improved method are good.CONCLUSION The problem of the old method was solved with this improved method and have a universal significance for the determination of ointment preparation.
Citation: | YANG Xi-Xiang, GU Li. The improve of the method for determination compound fluocinonide ointment[J]. Journal of Pharmaceutical Practice and Service, 2002, (3): 171-173. |