Studies on assay of roxithromycin in electron medicinal membrane of roxithromycin
- Received Date: 2002-04-22
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Key words:
- electron medicinal membrane /
- roxithromycin /
- HPLC /
- content determination
Abstract: OBJECTIVE To develop a method for assay of roxithromycin in electron medicinal membrane of roxithromycin. METHODS To use a HPLC method by YWG C18 column. The mobile phase was a mixture of acetonitrile-methano-l0.5% ammonium acetate(100:80:60),with the detection wavelength at 235 nm.RESULTS Precision and stability were fine. The linear correlation was observed from the concentrations of 0.3 to 1.7mg·ml-1(r=0.9998).The average recovery was 99.23%.Resolution bettween roxithromycin and other peaks met the requirements.CONCLUSION The method is convenient, selective and reproducible.
Citation: | Wang Xiao-bo, Wang Jing-guo, Xi Rong-gang. Studies on assay of roxithromycin in electron medicinal membrane of roxithromycin[J]. Journal of Pharmaceutical Practice and Service, 2002, (5): 293-295. |