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Volume 21 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2003  >  (5): 283-286

ZHU Ai-min, LI Zhen-ling, LI Sheng-gang, YANG Xiao-feng. The research on toxicity test of seed oil of spine date[J]. Journal of Pharmaceutical Practice and Service, 2003, (5): 283-286.
Citation: ZHU Ai-min, LI Zhen-ling, LI Sheng-gang, YANG Xiao-feng. The research on toxicity test of seed oil of spine date[J]. Journal of Pharmaceutical Practice and Service, 2003, (5): 283-286.
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The research on toxicity test of seed oil of spine date

  • 1.

    Qingdao Drug Control Institute, Qingdao 266071, China

  • 2.

    China Ocean University, Qingdao 266073 , China

  • Received Date: 2003-03-25
  • OBJECTIVE: To evaluate medinal safety of oil of spine date seed . METHODS: Acute toxicity test and blood biochemistry test were used. RESULTS: We did not get LD50 to mouse and rat, and no chronic toxicity to rabbit skin. The weight and blood index on rat were not remarkable from contral group, We did not find pathology difference on heart, liver, lung, kidney, adrenal gland, thymus, spermary, matrix, ovary etc by general view and pathology slice. No evidence irritation reaction had happened to guinea pig skin、rabbit eyes and part of cunt. We had not found hypersensitivity guinea pig skin. CONCLUSION: The seed oil of spine date is safe on medinal usage.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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The research on toxicity test of seed oil of spine date

  • 1. Qingdao Drug Control Institute, Qingdao 266071, China
  • 2. China Ocean University, Qingdao 266073 , China
  • Received Date: 2003-03-25

Abstract: OBJECTIVE: To evaluate medinal safety of oil of spine date seed . METHODS: Acute toxicity test and blood biochemistry test were used. RESULTS: We did not get LD50 to mouse and rat, and no chronic toxicity to rabbit skin. The weight and blood index on rat were not remarkable from contral group, We did not find pathology difference on heart, liver, lung, kidney, adrenal gland, thymus, spermary, matrix, ovary etc by general view and pathology slice. No evidence irritation reaction had happened to guinea pig skin、rabbit eyes and part of cunt. We had not found hypersensitivity guinea pig skin. CONCLUSION: The seed oil of spine date is safe on medinal usage.

ZHU Ai-min, LI Zhen-ling, LI Sheng-gang, YANG Xiao-feng. The research on toxicity test of seed oil of spine date[J]. Journal of Pharmaceutical Practice and Service, 2003, (5): 283-286.
Citation: ZHU Ai-min, LI Zhen-ling, LI Sheng-gang, YANG Xiao-feng. The research on toxicity test of seed oil of spine date[J]. Journal of Pharmaceutical Practice and Service, 2003, (5): 283-286.
shu

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