Determination and study on content and stability of matrine in compound ma-trine capsule
- Received Date: 2001-03-08
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Key words:
- thin-layer chromatography-ultraviolet pectrophotometry /
- matrine /
- compound matrine capsule /
- classical isothermal method
Abstract: Objective To determine the matrine in compound matrine capsule and to investigate the stability of matrine in compound matrine capsule, so as to establish the quality standard to control the quality of the drug.Methods The matrine was determined by thin-layer chromatography-ultraviolet pectrophotometry and classical isothermal method.Results The linear range was 1.512~7.560μg/mL.The average recovery rate was 97.29%,RSD =2.84%.The expiry date of matrine in compound matrine capsule was about 1.2 years.Conclusion; The method is simple, quick and accurate, also can be used as the quality control method for the compound matrine capsule.And the results showed that matrine in compound matrine capsule was stable.
Citation: | DING Qing-long, YUN Hong-wei. Determination and study on content and stability of matrine in compound ma-trine capsule[J]. Journal of Pharmaceutical Practice and Service, 2005, (1): 20-24. |