Determination of compound dexamethason acetate liniment
- Received Date: 2005-02-18
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Key words:
- first derivative spectrometry /
- seeable spectrometry /
- compound dexamethason acetate liniment /
- camphor /
- dexamethason acetate /
- determination of content
Abstract: Objective To establish a quantitative analysis method for camphor and dexamethason acetate in compound dexametha son acetate liniment.Methods The camphor was determined directly at 305nm by first derivative spectrometry.The dexamethason acetate was determined at 485nm by seeable spectrometry.Results The calibra-tion curve of camphor was linear in the range from 1.62-3.22mg/mL with r=0.999 4,the average recovery and relative standard deviation were 99.89% and 0.34% respectively.The calibration curve of dexamethason acetate was linear in the range from 122.04-227.81μg/mL with r= 0.9997, the average recovery and RSD were 99.18% and 1.32% respectively.Conclusions The method is simple, rapid and accurate.It can be used to control the quality of compound dexame-thason acetate liniment.
Citation: | GU Wei-ying, ZHANG He-ping, HUANG Wei-fen, GU Hong-jun. Determination of compound dexamethason acetate liniment[J]. Journal of Pharmaceutical Practice and Service, 2005, (3): 167-169. |