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Volume 23 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2005  >  (4): @-@

MAO Gui-fu. Determination of salicylic acid and phenol in salicylic acid and phenol lotion by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2005, (4): @-@.
Citation: MAO Gui-fu. Determination of salicylic acid and phenol in salicylic acid and phenol lotion by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2005, (4): @-@.
shu

Determination of salicylic acid and phenol in salicylic acid and phenol lotion by HPLC

  • Department of Pharmacy, Railway Central Hospital of Liuzhou, Liuzhou 545007, China

  • Received Date: 2004-09-01
  • Objective To establish a HPLC method for the determination of salicylic acid and phenol in salicylic acid and phenol lotion.Methods Shim-pack CLC-CN column was used, and the column temperature was maintained at 40℃.The mobile phase was consisted of methanol and water(28 : 72), and adjusted to pH 5.0 by glacial acetic acid.The flow rate was 0.9mL/min.The detection wavelength was 277nm.Results The linear range of standard curve of salicylic acid and phenol were between 10.0-500.0 μg/ mL(r=0.999 9) and between 10.0-200.0μg/mL(r= 0.999 9), respectively.The average recovery was 100.9% and 100.8%. Conclusion The method was simple, accurate.It can be used for the quality control of salicylic acid and phenol lotion.
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Determination of salicylic acid and phenol in salicylic acid and phenol lotion by HPLC

  • Department of Pharmacy, Railway Central Hospital of Liuzhou, Liuzhou 545007, China
  • Received Date: 2004-09-01

Abstract: Objective To establish a HPLC method for the determination of salicylic acid and phenol in salicylic acid and phenol lotion.Methods Shim-pack CLC-CN column was used, and the column temperature was maintained at 40℃.The mobile phase was consisted of methanol and water(28 : 72), and adjusted to pH 5.0 by glacial acetic acid.The flow rate was 0.9mL/min.The detection wavelength was 277nm.Results The linear range of standard curve of salicylic acid and phenol were between 10.0-500.0 μg/ mL(r=0.999 9) and between 10.0-200.0μg/mL(r= 0.999 9), respectively.The average recovery was 100.9% and 100.8%. Conclusion The method was simple, accurate.It can be used for the quality control of salicylic acid and phenol lotion.

MAO Gui-fu. Determination of salicylic acid and phenol in salicylic acid and phenol lotion by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2005, (4): @-@.
Citation: MAO Gui-fu. Determination of salicylic acid and phenol in salicylic acid and phenol lotion by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2005, (4): @-@.
shu

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