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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2006  >  (1): 22-25

ZHANG Liang, ZHAO Yi-hua. Determination of the entrapment efficiency of silybin liposomes by first derivative spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2006, (1): 22-25.
Citation: ZHANG Liang, ZHAO Yi-hua. Determination of the entrapment efficiency of silybin liposomes by first derivative spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2006, (1): 22-25.
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Determination of the entrapment efficiency of silybin liposomes by first derivative spectrometry

  • Department of Pharmacy, No.515 Hospital of PLA, Jiangyin 214431, China

  • Received Date: 2005-03-17
  • Objective :To establish a method for the determination of the entrapment efficiency of silybin liposomes. Methods :First derivative spectrometry was established.The two middle wavelengths were 275nm and 317nm.The detection wavelengths were 274,276, 316 and 318nm,respectively. Results :The calibration curve of silybin was linear in the range of 0-30.3uuuuuuuuuuuug/mL and the correlation coefficient was 0.9995.The average recovery and relative standard deviation were 100.8% and 0.8%,respectively. Conclusion :The method is practicable.
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Determination of the entrapment efficiency of silybin liposomes by first derivative spectrometry

  • Department of Pharmacy, No.515 Hospital of PLA, Jiangyin 214431, China
  • Received Date: 2005-03-17

Abstract: Objective :To establish a method for the determination of the entrapment efficiency of silybin liposomes. Methods :First derivative spectrometry was established.The two middle wavelengths were 275nm and 317nm.The detection wavelengths were 274,276, 316 and 318nm,respectively. Results :The calibration curve of silybin was linear in the range of 0-30.3uuuuuuuuuuuug/mL and the correlation coefficient was 0.9995.The average recovery and relative standard deviation were 100.8% and 0.8%,respectively. Conclusion :The method is practicable.

ZHANG Liang, ZHAO Yi-hua. Determination of the entrapment efficiency of silybin liposomes by first derivative spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2006, (1): 22-25.
Citation: ZHANG Liang, ZHAO Yi-hua. Determination of the entrapment efficiency of silybin liposomes by first derivative spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2006, (1): 22-25.
shu

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