Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats
- Received Date: 2005-10-27
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Key words:
- Qingzhiyuan soft capsule /
- antioxidation /
- hyperlipidemia
Abstract: Objective : To study the effects of Qingzhiyuan soft capsule(QZY)on blood lipid and antioxidant activity in hyperlipi-demia rats. Methods : Fifty Wister rats were randomly divided into five groups according to body weight and serum cholesterol levels.They were fed one of five diets, a reference diet, a high fat supplemented diet and a high fat supplemented with 20mg/kg, 5mg/kg QZY, a positive diets.After three weeks, blood lipid and antioxidant activity were determined respectively. Results : Compared with model, QZY could reduced the serum TC, TG, LDL-C concentration, increased SOD and GSH-Px activities, decreased MDA level significantly(P<0.05). Conclusion : QZY might play an important role in preventing hyperlipidemia through its antioxidative effect.
Citation: | JIANG Tao, QIN Lu-ping, ZHENG Han-chen, HAN Ting. Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 81-83. |