Study on compatible stability of ampicloxacillin sodium for injection in five infusions
- Received Date: 2005-06-10
-
Key words:
- ampicloxacillin /
- ampicillin /
- cloxacillin /
- compatibility
Abstract: Objective : To investigate the compatible stability of ampicoxacillin sodium for injection in five infusions in different time and different temperature conditions. Methods : Ampicloxacillin sodium was dissolved in five infusions.Ampicillin and cloxacillin in ampicloxacillin sodium for injection were determined by HPLC,and the color changes of all infusions were observed. Results : The ampicillin and eloxacillin contents in ampicloxacillin sodium for injection declined with time and temperature increased.The most distinct were 5% glucose injection. Concision : Ampicloxacillin sodium for injection wasn't stable in 5% glucose, gluscose and sodium chloride injection.
Citation: | ZHANG Li-bin, ZHANG Xiao-qing, LIU Ming-zhong. Study on compatible stability of ampicloxacillin sodium for injection in five infusions[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 86-89. |