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Volume 24 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2006  >  (3): 142-144

CHU Gang, GAO Jing, LU Ying, DING Xue-Ying, GAO Shen. Pseudo-ternary phase diagrams of lecithin liquid crystal[J]. Journal of Pharmaceutical Practice and Service, 2006, (3): 142-144.
Citation: CHU Gang, GAO Jing, LU Ying, DING Xue-Ying, GAO Shen. Pseudo-ternary phase diagrams of lecithin liquid crystal[J]. Journal of Pharmaceutical Practice and Service, 2006, (3): 142-144.
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Pseudo-ternary phase diagrams of lecithin liquid crystal

  • Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2005-11-01
  • Objective : To construct pseudo-ternary phase diagrams of liquid crystal (LC) with lecithin of various purity and various ratio of lecithin to alcohol (Km). Methods : LC was prepared with lecithin of various purity as surfactant, isopropyl myristate as oil phase and anhydrous alcohol as co-surfactant. The LC configuration was determined with self-made polarization microscope. Results : The liquid crystal formation region was observed light with the polarization microscope. No liquid crystal appeared when the Km was 1 : 4, and in the same condition of 25℃ and Km, the liquid crystal formation region was larger with the lecithin purity increasing. At the same time, the changeable region of water proportion was also larger with the Km increasing. Conclusion : Constructing pseudo-ternary phase diagrams to discribe the factors of liquid crystal configuration is precise and simple.
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Pseudo-ternary phase diagrams of lecithin liquid crystal

  • Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2005-11-01

Abstract: Objective : To construct pseudo-ternary phase diagrams of liquid crystal (LC) with lecithin of various purity and various ratio of lecithin to alcohol (Km). Methods : LC was prepared with lecithin of various purity as surfactant, isopropyl myristate as oil phase and anhydrous alcohol as co-surfactant. The LC configuration was determined with self-made polarization microscope. Results : The liquid crystal formation region was observed light with the polarization microscope. No liquid crystal appeared when the Km was 1 : 4, and in the same condition of 25℃ and Km, the liquid crystal formation region was larger with the lecithin purity increasing. At the same time, the changeable region of water proportion was also larger with the Km increasing. Conclusion : Constructing pseudo-ternary phase diagrams to discribe the factors of liquid crystal configuration is precise and simple.

CHU Gang, GAO Jing, LU Ying, DING Xue-Ying, GAO Shen. Pseudo-ternary phase diagrams of lecithin liquid crystal[J]. Journal of Pharmaceutical Practice and Service, 2006, (3): 142-144.
Citation: CHU Gang, GAO Jing, LU Ying, DING Xue-Ying, GAO Shen. Pseudo-ternary phase diagrams of lecithin liquid crystal[J]. Journal of Pharmaceutical Practice and Service, 2006, (3): 142-144.
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