Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 25 Issue 3
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2007  >  (3): 162-164

LIU Hong-ju, YAN Chong. Determination of retinol palmitate,colecalciferol and vitamin E acetate in multi-vitamin injection by solid phase extraction and RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2007, (3): 162-164.
Citation: LIU Hong-ju, YAN Chong. Determination of retinol palmitate,colecalciferol and vitamin E acetate in multi-vitamin injection by solid phase extraction and RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2007, (3): 162-164.
shu

Determination of retinol palmitate,colecalciferol and vitamin E acetate in multi-vitamin injection by solid phase extraction and RP-HPLC

  • School of Pharmacy, Guangdong Medical College, Dongguan 523808, China

  • Received Date: 2006-06-27
  • Objective: To establish nonaqueous RP-HPLC to determine retinol palmitate、colecalciferol and vitamin E acetate in multi-vitamin injection simultaneously. Methods: The fat vitamins were extracted by SPE; The determination was performed on Warters C18 column (150×4.6 mm, 5.0 μm) with the mobile phase of acetonitrile-methanol-dichloromethane(702010),at a flow rate of 1.0 mL/min and the detection wavelength of 265 nm.Results: In the linear range the correlation coefficients were all 0.999 9.The average recoveries of retinol palmitate、colecalciferol and vitamin E acetate were 99.1%, 100.6% and 99.2%, RSDwere 0.19%, 0.79% and 0.52%.Conclusion:The method is simple and rapid, suitable for the analysis of retinol palmitate,Colecalciferol and vitamin E acetate in multi-vitamin injection.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2478) PDF downloads(1117) Cited by()

Related
Proportional views

Determination of retinol palmitate,colecalciferol and vitamin E acetate in multi-vitamin injection by solid phase extraction and RP-HPLC

  • School of Pharmacy, Guangdong Medical College, Dongguan 523808, China
  • Received Date: 2006-06-27

Abstract: Objective: To establish nonaqueous RP-HPLC to determine retinol palmitate、colecalciferol and vitamin E acetate in multi-vitamin injection simultaneously. Methods: The fat vitamins were extracted by SPE; The determination was performed on Warters C18 column (150×4.6 mm, 5.0 μm) with the mobile phase of acetonitrile-methanol-dichloromethane(702010),at a flow rate of 1.0 mL/min and the detection wavelength of 265 nm.Results: In the linear range the correlation coefficients were all 0.999 9.The average recoveries of retinol palmitate、colecalciferol and vitamin E acetate were 99.1%, 100.6% and 99.2%, RSDwere 0.19%, 0.79% and 0.52%.Conclusion:The method is simple and rapid, suitable for the analysis of retinol palmitate,Colecalciferol and vitamin E acetate in multi-vitamin injection.

LIU Hong-ju, YAN Chong. Determination of retinol palmitate,colecalciferol and vitamin E acetate in multi-vitamin injection by solid phase extraction and RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2007, (3): 162-164.
Citation: LIU Hong-ju, YAN Chong. Determination of retinol palmitate,colecalciferol and vitamin E acetate in multi-vitamin injection by solid phase extraction and RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2007, (3): 162-164.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return