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Volume 25 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2007  >  (4): 222-223,260

QIN Zong-ling. Preparation and quality control of flurbiprofen liposomal gel[J]. Journal of Pharmaceutical Practice and Service, 2007, (4): 222-223,260.
Citation: QIN Zong-ling. Preparation and quality control of flurbiprofen liposomal gel[J]. Journal of Pharmaceutical Practice and Service, 2007, (4): 222-223,260.
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Preparation and quality control of flurbiprofen liposomal gel

  • Department of Pharmacy,Putuo District Central Hospital,Shanghai 200062,China

  • Received Date: 2007-03-06
  • Objective: To prepare flurbiprofen liposomal gel and to establish its quality control method. Methods: The liposome was prepared by ethanol injection method and the liposomal gel was prepared using mixing method.The content of flurbiprofen was de termined by HPLC.The entrapment efficiency of flurbiprofen liposome was determined by centrifugation. Results: The average recovery of flurbiprofen was(98.62±2.22)%.The entrapment efficiency of the liposome was(58.44±3.05)%.The pH vaule of the liposo- mal gel was between 6.0 and 7.0.The stability of the liposomal gel was good. Conclusion: This gel is feasible in preparation tech- nique,stable in quality,convenient and reliable in quality control method.
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Preparation and quality control of flurbiprofen liposomal gel

  • Department of Pharmacy,Putuo District Central Hospital,Shanghai 200062,China
  • Received Date: 2007-03-06

Abstract: Objective: To prepare flurbiprofen liposomal gel and to establish its quality control method. Methods: The liposome was prepared by ethanol injection method and the liposomal gel was prepared using mixing method.The content of flurbiprofen was de termined by HPLC.The entrapment efficiency of flurbiprofen liposome was determined by centrifugation. Results: The average recovery of flurbiprofen was(98.62±2.22)%.The entrapment efficiency of the liposome was(58.44±3.05)%.The pH vaule of the liposo- mal gel was between 6.0 and 7.0.The stability of the liposomal gel was good. Conclusion: This gel is feasible in preparation tech- nique,stable in quality,convenient and reliable in quality control method.

QIN Zong-ling. Preparation and quality control of flurbiprofen liposomal gel[J]. Journal of Pharmaceutical Practice and Service, 2007, (4): 222-223,260.
Citation: QIN Zong-ling. Preparation and quality control of flurbiprofen liposomal gel[J]. Journal of Pharmaceutical Practice and Service, 2007, (4): 222-223,260.
shu

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