Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry
- Received Date: 2007-12-11
- Rev Recd Date: 2007-01-15
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Key words:
- rabeprazole /
- canbon paste etectrode /
- anodic adsorptive voltammetry
Abstract: Objective: To establish a new method for the determination of rabeprazole. Methods: Anodic adsorptive voltammetry with a carbon paste electeode(CPE) was used. Rabeprazole was concentrated on the electrode and determined by adsorptive voltammetry in supporting solution of 1.8 mol/L H2SO4. Results: The anthodic peak potential of raberazole was at 0.498 V(vs.SCE). The peak currents were linear with the concentration of rabeprazole over the range of 4.15×10-7~3.73×10--6mol/L, with the detection limit 6.705×10--11 mol/L. Conclusion: This method is suitable for the determination of rabeprazole, and it is covenient and accurate.
Citation: | GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37. |