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CHEN Xiao-jin, LI Zhong-dong, DING Jun-jie, SHI Xiao-jin, XU Yi-xin. Establishment of the population pharmacokinetics model of sibutramine in Chinese healthy volunteers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 283-286.
Citation:
GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37.
Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry
Department of Pharmacy,Central Hospital of Yiyang of Hunan Province, Yiyang 413000,China
2.
Department of Pharmacy,Central Hospital of Yiyang of Hunan Province, Yiyang 413000,China
Received Date: 2007-12-11
Rev Recd Date:
2007-01-15
Abstract
Objective: To establish a new method for the determination of rabeprazole. Methods: Anodic adsorptive voltammetry with a carbon paste electeode(CPE) was used. Rabeprazole was concentrated on the electrode and determined by adsorptive voltammetry in supporting solution of 1.8 mol/L H2SO4. Results: The anthodic peak potential of raberazole was at 0.498 V(vs.SCE). The peak currents were linear with the concentration of rabeprazole over the range of 4.15×10-7~3.73×10--6mol/L, with the detection limit 6.705×10--11 mol/L. Conclusion: This method is suitable for the determination of rabeprazole, and it is covenient and accurate.
Abstract: Objective: To establish a new method for the determination of rabeprazole. Methods: Anodic adsorptive voltammetry with a carbon paste electeode(CPE) was used. Rabeprazole was concentrated on the electrode and determined by adsorptive voltammetry in supporting solution of 1.8 mol/L H2SO4. Results: The anthodic peak potential of raberazole was at 0.498 V(vs.SCE). The peak currents were linear with the concentration of rabeprazole over the range of 4.15×10-7~3.73×10--6mol/L, with the detection limit 6.705×10--11 mol/L. Conclusion: This method is suitable for the determination of rabeprazole, and it is covenient and accurate.
CHEN Xiao-jin, LI Zhong-dong, DING Jun-jie, SHI Xiao-jin, XU Yi-xin. Establishment of the population pharmacokinetics model of sibutramine in Chinese healthy volunteers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 283-286.
Citation:
GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37.
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CHEN Xiao-jin, LI Zhong-dong, DING Jun-jie, SHI Xiao-jin, XU Yi-xin. Establishment of the population pharmacokinetics model of sibutramine in Chinese healthy volunteers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 283-286.
CHEN Xiao-jin, LI Zhong-dong, DING Jun-jie, SHI Xiao-jin, XU Yi-xin. Establishment of the population pharmacokinetics model of sibutramine in Chinese healthy volunteers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 283-286.