Optimization of extraction technology of baicalin in radix scutellariae by RP-HPLC
- Received Date: 2008-03-28
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Key words:
- radix scutellariae /
- baicalin /
- Orthogonal design /
- HPLC
Abstract: Objective:To study the extraction technology of baicalin in radix scutellariae.Methods:The L9(34) orthogonal table was employed to speculate the influence factors of the extraction by means of inspecting alcohol concentration,extracting time and sol- vent volumn,which were the major three influenec factors.Then intiutive analysis and variance analysis were used to review the index of baicalin contents,by which the optimum extraction technology could be selected.Results:The optimum extraction technology were 12 times of 50% alcohol,hot reflux extraction and extracting for 1 time and 3 hours each time.Conclusion:This optimum extradion process of baicalin in radix scutellariae is simple and repeatable and it can be used in industrial production.
Citation: | Zhang Feng-mei. Optimization of extraction technology of baicalin in radix scutellariae by RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (5): 359-361. |