Blending of crude Epimedium Brevicornum according to their HPLC fingerprints
- Received Date: 2008-05-04
-
Key words:
- blending /
- TCM /
- Epimedium Brevicornum /
- fingerprinting
Abstract: Objective: To find a new way of improving the quality of TCM,blendings of crude Epimedium Brevicornum from various sources were studied according to their Fingerprints. Methods: Systematic optimization was adopted to determine the mixing ratio of different kinds of non-genuine crude drugs in order to maximize the similarity,which is based on the cosine value between the fingerprints of genuine and non-genuine crude drugs respectively.Fingerprints data were collected after the blending. Results: The similarity of drugs was improved evidently,and it was in accordance with the calculation result. Conclusion: Quality improvement of TCM can be made by blending.Optimized blending of crude drugs might be an efficient method in making full use of the relatively inadequate TCM resources.
Citation: | WANG Bin, HUANG He-zhou, ZHU Zhen-yu, ZHANG Hai, JI Song-gang, CHAI Yi-feng. Blending of crude Epimedium Brevicornum according to their HPLC fingerprints[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 432-434,456. |