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JIANG Ren, LIU Gang, ZHANG Hua, CHANG Hua, TAN Sheng-jian. Determination of baicalin in Xiaoer Runfei Oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 435-437.
Citation: JIANG Ren, LIU Gang, ZHANG Hua, CHANG Hua, TAN Sheng-jian. Determination of baicalin in Xiaoer Runfei Oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 435-437.

Determination of baicalin in Xiaoer Runfei Oral liquid by HPLC

  • Received Date: 2007-08-03
  • Objective: To develop an HPLC quantitative method for the determination of baicalin in Xiaoer Runfei Oral liquid. Methods: HPLC system consisted an Agilent C18column(ZORBAX Eclipse XDB-C18,4.6 mm×150 mm,5μm)and a mixture of methanol-water-phosphoric acid(38:62:0.5)as mobile phase.The flow rate was 1.0 mL/min and was monitored at 278 nm. Results: The retention time of baicalin was 20.6 min.The regress equation for baicalin was Y=0.060 47X+1.131,r=0.999 9,and the linear range was 62.84~314.2μg/mL.The average recovery of baicalin was(n=6)103.3%,RSD 0.43%. Conclusion: The method was sensitive,time-saving and accurate.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Determination of baicalin in Xiaoer Runfei Oral liquid by HPLC

Abstract: Objective: To develop an HPLC quantitative method for the determination of baicalin in Xiaoer Runfei Oral liquid. Methods: HPLC system consisted an Agilent C18column(ZORBAX Eclipse XDB-C18,4.6 mm×150 mm,5μm)and a mixture of methanol-water-phosphoric acid(38:62:0.5)as mobile phase.The flow rate was 1.0 mL/min and was monitored at 278 nm. Results: The retention time of baicalin was 20.6 min.The regress equation for baicalin was Y=0.060 47X+1.131,r=0.999 9,and the linear range was 62.84~314.2μg/mL.The average recovery of baicalin was(n=6)103.3%,RSD 0.43%. Conclusion: The method was sensitive,time-saving and accurate.

JIANG Ren, LIU Gang, ZHANG Hua, CHANG Hua, TAN Sheng-jian. Determination of baicalin in Xiaoer Runfei Oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 435-437.
Citation: JIANG Ren, LIU Gang, ZHANG Hua, CHANG Hua, TAN Sheng-jian. Determination of baicalin in Xiaoer Runfei Oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 435-437.

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