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Volume 26 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (6): 441-443

HE Lei, SHI Qi-rong, LIU Run-hui, XU Xi-ke, SHEN Yun-heng, LI Hui-liang, ZHANG Wei-dong. Coumarins from the branches of Daphne genkwa[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 441-443.
Citation: HE Lei, SHI Qi-rong, LIU Run-hui, XU Xi-ke, SHEN Yun-heng, LI Hui-liang, ZHANG Wei-dong. Coumarins from the branches of Daphne genkwa[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 441-443.
shu

Coumarins from the branches of Daphne genkwa

  • Department of Phytochemistry, School of Pharmacy,Second Military Medical University,Shanghai 200433,China

  • Received Date: 2008-03-24
  • Objective: To study the chemical constituents of the branches of Daphne genkwa Sieb.et Zucc. Methods: Column chromatography on Silica gel and Sephadex LH-20,and recrystallization were used for the isolation and purification of the constituents. The structures were identified on the basis of spectral analysis and chemical evidences. Results: From the crude CHCl3 fraction of the EtOH extract of the branches of D.genkwa,6 coumarins were isolated and identified,which were umbelliferone（1）,daphnoretin （2）,daphnetin（3）,edgeworthin（4）,edgeworin（5）,and umbelliferone-7-O-β-D-glycoside（6）. Conclusion: ICompounds 3～6 were isolated and identified from the branches of Daphne genkwa for the first time.
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Coumarins from the branches of Daphne genkwa

  • Department of Phytochemistry, School of Pharmacy,Second Military Medical University,Shanghai 200433,China
  • Received Date: 2008-03-24

Abstract: Objective: To study the chemical constituents of the branches of Daphne genkwa Sieb.et Zucc. Methods: Column chromatography on Silica gel and Sephadex LH-20,and recrystallization were used for the isolation and purification of the constituents. The structures were identified on the basis of spectral analysis and chemical evidences. Results: From the crude CHCl3 fraction of the EtOH extract of the branches of D.genkwa,6 coumarins were isolated and identified,which were umbelliferone（1）,daphnoretin （2）,daphnetin（3）,edgeworthin（4）,edgeworin（5）,and umbelliferone-7-O-β-D-glycoside（6）. Conclusion: ICompounds 3～6 were isolated and identified from the branches of Daphne genkwa for the first time.

HE Lei, SHI Qi-rong, LIU Run-hui, XU Xi-ke, SHEN Yun-heng, LI Hui-liang, ZHANG Wei-dong. Coumarins from the branches of Daphne genkwa[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 441-443.
Citation: HE Lei, SHI Qi-rong, LIU Run-hui, XU Xi-ke, SHEN Yun-heng, LI Hui-liang, ZHANG Wei-dong. Coumarins from the branches of Daphne genkwa[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 441-443.
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