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LI Ya-nan, LI Yao-wu, ZHEN Can-hui, LU jia-guo, TANG Hui, ZHANG Jue, ZHOU You-jun. Study on the synthesis of replaced imidazole[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 447-449.
Citation: LI Ya-nan, LI Yao-wu, ZHEN Can-hui, LU jia-guo, TANG Hui, ZHANG Jue, ZHOU You-jun. Study on the synthesis of replaced imidazole[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 447-449.

Study on the synthesis of replaced imidazole

  • Received Date: 2008-09-28
  • Objective: To optimize the synthesis of replaced imidazole. Methods: Orthogonal experimental design was used and the influence of temperature,reactant ratio and solvent on the yield were investigated. Results: Reactant ratio was more important than the others.The yield was improved from less than 10%to 42.5%. Conclusion: The optimal preparation procedure is stable and available for industrial production.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on the synthesis of replaced imidazole

Abstract: Objective: To optimize the synthesis of replaced imidazole. Methods: Orthogonal experimental design was used and the influence of temperature,reactant ratio and solvent on the yield were investigated. Results: Reactant ratio was more important than the others.The yield was improved from less than 10%to 42.5%. Conclusion: The optimal preparation procedure is stable and available for industrial production.

LI Ya-nan, LI Yao-wu, ZHEN Can-hui, LU jia-guo, TANG Hui, ZHANG Jue, ZHOU You-jun. Study on the synthesis of replaced imidazole[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 447-449.
Citation: LI Ya-nan, LI Yao-wu, ZHEN Can-hui, LU jia-guo, TANG Hui, ZHANG Jue, ZHOU You-jun. Study on the synthesis of replaced imidazole[J]. Journal of Pharmaceutical Practice and Service, 2008, (6): 447-449.

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