Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts
- Received Date: 2009-03-18
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Key words:
- lovastatin /
- oxidized low density lipoprotein /
- hypoxia inducible factor 1 /
Abstract: Objective :To explore the rule of secretion of IL-10 stimulated sulfur mustard in human fibroblasts. Methods :The ELISA was used to detect the relationship between dose and efficacy,time course and efficacy of which sulfur mustard adjusted the secretion of IL-10. Results :A portion of IL-10 could be secreted by the human fibroblasts.The secretion of IL-10 could be significantly stimulated after the function of sulfur mustard which depended on the time-course and dosage. Conclusion :The therapeutic mechanism of sulfur mustard to Psoriasis might related with the promotion of the secretion of IL-10.
Citation: | TIAN Jin, LU Jian, YANG Ji-shun, HU Jin-hong. Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 177-178,188. |