Optimization of extraction technology for Sanhuang Jiedu cream by orthogonal test
- Received Date: 2009-09-08
- Rev Recd Date: 2009-11-05
-
Key words:
- Sanhuang Jiedu cream /
- orthogonal test /
- extraction technology
Abstract: Objective To optimize the extraction technology for Sanhuang Jiedu cream. Methods The optimum extraction technology for Sanhuang Jiedu cream was investigated by the L9(34) orthogonal test with the total amount of the dry extract and the content of berberine hydrochloride as technology index.The influence factors including the concentration of ethanol,solvent ratio,extraction times,time length of extraction. Results The optimum extraction technology was: the solid-liquid ratio was 110;the concentration of ethanol was 70%;the refluxing extraction was carried out for 3 times(1hours/time). Conclusion The optimum extraction technology for Sanhuang Jiedu cream is stable and feasible.
Citation: | LIU Jun, DU Jian-ping, SHI Zhi-qi. Optimization of extraction technology for Sanhuang Jiedu cream by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(2): 116-117,133. |