Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 28 Issue 5
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(5): 331-333

Wang Wei, Wang Xiao-hua, Zhang Xiao-jie, Chen Jian-ming. Study on pharmacokinetics of compound Danshen dropping pills of new matrix[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 331-333.
Citation: Wang Wei, Wang Xiao-hua, Zhang Xiao-jie, Chen Jian-ming. Study on pharmacokinetics of compound Danshen dropping pills of new matrix[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 331-333.
shu

Study on pharmacokinetics of compound Danshen dropping pills of new matrix

  • 1.

    455th Hospital of PLA,Shanghai 200052,China;School of Pharmacy,Second Military Medical University,Shanghai 200433,China

  • 2.

    202th Hospital of PLA,Shenyang 110003,China

  • 3.

    Drug Supply Station of General logistics of PLA,Beijing 100071,China

  • 4.

    School of Pharmacy,Second Military Medical University,Shanghai 200433,China

  • Received Date: 2010-02-01
  • Rev Recd Date: 2010-06-24
  • Objective To study the pharmacokinetics of compound Danshen dropping pills of new matrix. Methods HPLC was used as a detection method.New Zealand rabbits were taken as experimental animals.The compound Danshen dropping pills sold in market were taken as comparison products. Results There was a significant difference of Cmax and Ka between two kinds of pills(P<0.05).There was no significant different of tpeak、AUC、t1/2β,MRT and VRT.The relative bioavailability of compound Danshen dropping pills of new matrix was 114.5%. Conclusion The absorption rate constant and Cpeak of compound Danshen dropping pills of new matrix were much higher than the pills sold on the market.New matrix could improve the performance of quick Results and high efficiency of the dropping pills.The peak-time,the time of maintaining effective concentration and the elimination of drugs were same as old ones on the whole.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2432) PDF downloads(618) Cited by()

Related
Proportional views

Study on pharmacokinetics of compound Danshen dropping pills of new matrix

  • 1. 455th Hospital of PLA,Shanghai 200052,China;School of Pharmacy,Second Military Medical University,Shanghai 200433,China
  • 2. 202th Hospital of PLA,Shenyang 110003,China
  • 3. Drug Supply Station of General logistics of PLA,Beijing 100071,China
  • 4. School of Pharmacy,Second Military Medical University,Shanghai 200433,China
  • Received Date: 2010-02-01
  • Rev Recd Date: 2010-06-24

Abstract: Objective To study the pharmacokinetics of compound Danshen dropping pills of new matrix. Methods HPLC was used as a detection method.New Zealand rabbits were taken as experimental animals.The compound Danshen dropping pills sold in market were taken as comparison products. Results There was a significant difference of Cmax and Ka between two kinds of pills(P<0.05).There was no significant different of tpeak、AUC、t1/2β,MRT and VRT.The relative bioavailability of compound Danshen dropping pills of new matrix was 114.5%. Conclusion The absorption rate constant and Cpeak of compound Danshen dropping pills of new matrix were much higher than the pills sold on the market.New matrix could improve the performance of quick Results and high efficiency of the dropping pills.The peak-time,the time of maintaining effective concentration and the elimination of drugs were same as old ones on the whole.

Wang Wei, Wang Xiao-hua, Zhang Xiao-jie, Chen Jian-ming. Study on pharmacokinetics of compound Danshen dropping pills of new matrix[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 331-333.
Citation: Wang Wei, Wang Xiao-hua, Zhang Xiao-jie, Chen Jian-ming. Study on pharmacokinetics of compound Danshen dropping pills of new matrix[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 331-333.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return