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Volume 28 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(5): 352-353,380

XIA Ai-jun, ZHANG Qi, LIANG Yuan. Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 352-353,380.
Citation: XIA Ai-jun, ZHANG Qi, LIANG Yuan. Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 352-353,380.
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Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice

  • Department of Pharmacy,303th Hospital of PLA,Nanning 530021,China

  • Received Date: 2010-04-22
  • Rev Recd Date: 2010-05-24
  • Objective To study the hepatoprotective effect of shugananlening extract against mice liver damage which induced by carbon tetrachloride(CCl4). Methods Acute chemical liver jnjury model was induced by CCl4 in mice.The activities of ALT,AST in serum and the content of MDA,GSH,GSH-Px in liver were measured. Results Different dose of shugananlening extract significantly increased the content of GSH,GSH-Px in liver(P<0.01),decreased the activities of ALT,AST in serum and content of MDA in liver(P<0.05). Conclusion Shugananlening extract has a good protective effect on acute chemical liver injury in mice,which possibly due to the antioxidative capability of strengthening GSH system.
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Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice

  • Department of Pharmacy,303th Hospital of PLA,Nanning 530021,China
  • Received Date: 2010-04-22
  • Rev Recd Date: 2010-05-24

Abstract: Objective To study the hepatoprotective effect of shugananlening extract against mice liver damage which induced by carbon tetrachloride(CCl4). Methods Acute chemical liver jnjury model was induced by CCl4 in mice.The activities of ALT,AST in serum and the content of MDA,GSH,GSH-Px in liver were measured. Results Different dose of shugananlening extract significantly increased the content of GSH,GSH-Px in liver(P<0.01),decreased the activities of ALT,AST in serum and content of MDA in liver(P<0.05). Conclusion Shugananlening extract has a good protective effect on acute chemical liver injury in mice,which possibly due to the antioxidative capability of strengthening GSH system.

XIA Ai-jun, ZHANG Qi, LIANG Yuan. Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 352-353,380.
Citation: XIA Ai-jun, ZHANG Qi, LIANG Yuan. Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(5): 352-353,380.
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