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Volume 28 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(6): 422-425

LAN Zhi-hui, LIU Yan-tong, HE Yi-yang, LI Mao-xing, DU Qing-yun, JIA Zheng-ping. Study on the formulation and stability of the total flavones cream of Oxytropis falcata[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 422-425.
Citation: LAN Zhi-hui, LIU Yan-tong, HE Yi-yang, LI Mao-xing, DU Qing-yun, JIA Zheng-ping. Study on the formulation and stability of the total flavones cream of Oxytropis falcata[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 422-425.
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Study on the formulation and stability of the total flavones cream of Oxytropis falcata

  • 1.

    School of Pharmacy,Lanzhou University,Lanzhou 730000,China;Department of Pharmacy,Lanzhou General Hospital of PLA,Lanzhou 730050,China

  • 2.

    Department of Pharmacy,Lanzhou General Hospital of PLA,Lanzhou 730050,China

  • 3.

    Department of Pharmacy,The 175th Hospital of PLA,Zhangzhou 350005,China

  • 4.

    School of Pharmacy,Lanzhou University,Lanzhou 730000,China;Department of Pharmacy,Lanzhou General Hospital of PLA,Lanzhou 730050,China

  • Received Date: 2010-01-28
  • Rev Recd Date: 2010-06-16
  • Objective To study the formulation and stability of the total flavonoids cream from Oxytropis falcata. Methods The oil in water(O/W) cream matrixes with different compositions were studied.The quality and stability of the creams were evaluated by appearance inspection,microscopic observation and content alteration. Results The optimal cream bases contains: stearic acid 3 g,white vaseline 3 g,satiric-glycerol ester 1 g,span-60 0.8 g,liquid paraffine 4.5 g as the oil phase,tween-80 2.5 g,glycerol 5 g,methyl p-hydroxybenzoate 0.1 g,and distilled water 40 ml as the aqueous phase.The cream possessed the best character of lubrication,exquisition,stability and was easy to be used and cleaned. Conclusion The formulation of the total flavonoids cream of Oxytropis falcata was optimized with stable quality.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on the formulation and stability of the total flavones cream of Oxytropis falcata

  • 1. School of Pharmacy,Lanzhou University,Lanzhou 730000,China;Department of Pharmacy,Lanzhou General Hospital of PLA,Lanzhou 730050,China
  • 2. Department of Pharmacy,Lanzhou General Hospital of PLA,Lanzhou 730050,China
  • 3. Department of Pharmacy,The 175th Hospital of PLA,Zhangzhou 350005,China
  • 4. School of Pharmacy,Lanzhou University,Lanzhou 730000,China;Department of Pharmacy,Lanzhou General Hospital of PLA,Lanzhou 730050,China
  • Received Date: 2010-01-28
  • Rev Recd Date: 2010-06-16

Abstract: Objective To study the formulation and stability of the total flavonoids cream from Oxytropis falcata. Methods The oil in water(O/W) cream matrixes with different compositions were studied.The quality and stability of the creams were evaluated by appearance inspection,microscopic observation and content alteration. Results The optimal cream bases contains: stearic acid 3 g,white vaseline 3 g,satiric-glycerol ester 1 g,span-60 0.8 g,liquid paraffine 4.5 g as the oil phase,tween-80 2.5 g,glycerol 5 g,methyl p-hydroxybenzoate 0.1 g,and distilled water 40 ml as the aqueous phase.The cream possessed the best character of lubrication,exquisition,stability and was easy to be used and cleaned. Conclusion The formulation of the total flavonoids cream of Oxytropis falcata was optimized with stable quality.

LAN Zhi-hui, LIU Yan-tong, HE Yi-yang, LI Mao-xing, DU Qing-yun, JIA Zheng-ping. Study on the formulation and stability of the total flavones cream of Oxytropis falcata[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 422-425.
Citation: LAN Zhi-hui, LIU Yan-tong, HE Yi-yang, LI Mao-xing, DU Qing-yun, JIA Zheng-ping. Study on the formulation and stability of the total flavones cream of Oxytropis falcata[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 422-425.
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